Notice Number: NOT-HL-10-110

Key Dates
Release Date:  May 18, 2010

Issued by
National Heart, Lung, and Blood Institute (NHLBI), (http://www.nhlbi.nih.gov)

Purpose

On March 15, 2010, the NHLBI issued a Funding Opportunity Announcement (FOA): RFA-HL-11-006, Next Generation Genetic Association Studies (U01), http://grants1.nih.gov/grants/guide/rfa-files/RFA-HL-11-006.html.

 As a result of discussions with potential applicants, we are providing a list of Frequently Asked Questions (FAQs) and answers as well as clarification of the grant application format.

The FAQs for this FOA can be found at: http://www.nhlbi.nih.gov/funding/inits/docs/NextGenFAQ.pdf. This information may be updated periodically without additional notice.  NHLBI staff will also respond to questions submitted by potential applicants who contact the program, grants management, and review staff listed in the FOA in the Agency Contacts section.

Page Limits:  Grant applicants may propose phases I-III or phases II-III.  If phases I-III are proposed, the application may be a total of 36 pages in length (12 pages for each phase).  If only phases II-III are proposed, the application may be a total of 24 pages in length. 

Abstract:  The abstract should address all phases and provide a unified summary of all phases of the proposal. 

Specific Aims:  One set of Specific Aims should be provided for the entire study.  This will not count toward the page limit. The specific aims for each phase should provide a brief description of the overall aims of the application and a detailed description of the specific aims for the given phase.  The overall aims of the application may be repeated in the specific aims for each phase. 

Delineating phases within the Research Plan:  Applicants should use headings to clearly label each phase within the research plan.  Each phase will have a Specific Aims section.

Appendices:  Information provided in Appendices should be supplemental to topics discussed in the Research Plan.  The Research Plan should provide sufficient information for the reviewer to understand without reading the Appendices.

The following is an example of organization for a phase I-III proposal:

Project Description / Abstract – entire study
Specific Aims – entire study (1 page)
Research Plan (must not exceed 36 pages; 12 pages per phase)
            Background and Significance – entire study
            Preliminary Studies – entire study
                        Research Design and Methods Phase I
                                    Specific Aims Phase I
                                    Milestones Phase I
                        Research Design and Methods Phase II
                                    Specific Aims Phase II
                                    Milestones Phase II
                        Research Design and Methods Phase III
                                    Specific Aims Phase III
                                    Milestones Phase III

All other aspects of the FOA remain unchanged.

Inquiries

Interested parties may contact: Cashell Jaquish, Ph.D.

Contact information
Cashell E. Jaquish, Ph.D.
Division of Cardiovascular Sciences
National Heart, Lung, and Blood Institute
National Institutes of Health
6701 Rockledge Drive  MSC 7936
Suite 10018
Bethesda, MD 20892-7936
EXPRESS/COURIER:  Rockville, MD 20852
Phone:  (301) 435-0447; Fax:  (301) 480-1455
E-mail:  cj68r@nih.gov

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

	Office of Extramural Research (OER)			National Institutes of Health (NIH) 9000 Rockville Pike Bethesda, Maryland 20892			Department of Health and Human Services (HHS)
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