Notice of Community-Responsive Interventions to Reduce Cardiovascular Risk in American Indians and Alaska Natives

Notice Number: NOT-HL-06-107

Key Dates
Release Date: October 7, 2005

Issued by
National Heart, Lung, and Blood Institute (NHLBI), (

The purpose of this Notice is to announce the NHLBI's intention to issue a Request for Applications (RFA) in the fall of 2005 to fund five-year studies in American Indian/Alaskan Native (AI/AN) communities to test the effectiveness of behavioral interventions to promote the adoption of healthy lifestyles and/or improve behaviors related to cardiovascular (CV) risk, such as weight reduction, regular physical activity, and smoking cessation. These behaviors and lifestyles are known to affect biological cardiovascular risk factors, such as hypertension, dyslipidemia, obesity, glucose intolerance, and diabetes. A central feature of this project is to develop and test culturally appropriate interventions that could be incorporated into clinical programs of the community health care systems or delivered through public-health approaches in Native communities. The interventions tested should be sustainable and capable of being disseminated to other Native communities after termination of research support. The receipt date for applications would be in the spring of 2006.

This RFA may be of interest to researchers with expertise in the areas of behavioral sciences, prevention research, dietary and nutritional sciences, exercise science, minority health, epidemiology, biostatistics, and cardiology. Experience with controlled community studies is desirable, but not required. Applications must include evidence of 1) strong scientific capabilities and 2) evidence of community involvement and support. Applications that represent a partnership between a tribe or community and a research organization should include a resolution from the tribal or community government specifying that the community or tribe agrees to participate as a partner in the project and will strongly support the project for its entire duration.

This Notice encourages investigators who believe that they have sufficient expertise and resources to form these collaborative teams to begin considering applying for this RFA.

This RFA will be a reissue and modification of RFA-HL-04-023, which was previously released April 28, 2004 .


Interested parties may contact:

Jared B. Jobe, Ph.D.
Division of Epidemiology and Clinical Applications
National Heart, Lung, and Blood Institute
6701 Rockledge Drive , Room 8122, MSC 7936
Bethesda , MD 20892-7936
Telephone: (301) 435-0407
FAX: (301) 480-1773

Weekly TOC for this Announcement
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