Notice Number: NOT-HG-11-023
Release Date: June 14, 2011
National Human Genome Research Institute (NHGRI)
The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for existing pediatric biorepositories with genome-wide genotyping data to become part of the Electronic Medical Records and Genomic Research (eMERGE) Network, Phase II. Further details of eMERGE Phase II are available in RFA-HG-10-009, http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-10-009.html .
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.
The FOA is expected to be published in Summer, 2011, with an expected receipt date in Fall, 2011.
This FOA will utilize the U01 activity code. Details of the planned FOA are provided below.
Research Initiative Details
This Notice encourages investigators with expertise and insights into this area of conducting genomic research in pediatric biorepositories with electronic medical records and genome-wide genotyping data, and incorporating genomic knowledge into pediatric clinical research and ongoing pediatric clinical care, to begin to consider applying for this new FOA.
The goals of this initiative are to build upon the eMERGE Phase I experience in defining phenotypes from electronic medical records (EMRs), conducting genome-wide association studies, reducing risks to patient privacy from the sharing of EMR data, and developing consent and community consultation procedures for conducting such research to begin to incorporate genomic research results into pediatric clinical care. Among the areas of research encouraged in this initiative are expanding and validating the eMERGE "electronic phenotyping" library; expanding the number and diversity of participating eMERGE sites to include children and under-represented minorities; and incorporating genome-wide association genotyping information into EMRs, where feasible, for improving genetic risk assessment, prevention, diagnosis, treatment, and/or accessibility of genomic medicine.
APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.
Please direct all inquiries to:
Rongling Li, MD, PhD
Office of Population Genomics
National Human Genome Research Institute
5635 Fishers Lane
Suite 3058, MSC 9305
Bethesda, MD 20892-9305 (U.S. Postal Service Express or regular mail
Rockville, MD 20852 (FedEx/UPS/courier service; non-USPS service)
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
Office of Extramural
National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
Department of Health
and Human Services (HHS)
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