INDO-US PROGRAM ON MATERNAL AND CHILD HEALTH AND HUMAN DEVELOPMENT RESEARCH RELEASE DATE: April 22, 2003 NOTICE: NOT-HD-03-010 National Institute of Child Health and Human Development (NICHD) (http://www.nichd.nih.gov/) The Republic of India and the United States of America share a strong commitment to improve the health and well being of women, children, and adolescents through the expansion of cooperative biomedical and behavioral research. Although the health of women, children, and adolescents has improved significantly in both countries, it is recognized that important research questions remain to be answered in order to achieve additional reductions in morbidity and mortality. Building on a 30-year history of maternal and child health research cooperation, representatives of India and the United States signed a joint statement on June 13, 2000 to enhance this cooperation through an expanded program of Maternal and Child Health and Human Development Research. Program Structure The Indo-U.S. Program on Maternal and Child Health and Human Development Research (MCHDR) is administered by a Secretariat consisting of staff from the U.S. and Indian nodal agencies. The nodal agencies are the U.S. National Institute of Child Health and Human Development (NICHD) of the National Institutes of Health (NIH), U.S. Department of Health and Human Services, and the Indian Council for Medical Research (ICMR) of the Ministry of Health and Family Welfare. Indian collaborating agencies involved in support of this program include the Department of Women and Child Development, Ministry of Health and Family Welfare, the Department of Biotechnology, Ministry of Science and Technology, and the National AIDS Control Organization. U.S. collaborating agencies include other NIH Institutes and Centers, other Department of Health and Human Services agencies, the U.S. Agency for International Development (USAID), and the Agricultural Research Service (ARS) of the U.S. Department of Agriculture (USDA). In addition to the Secretariat, the overall scientific goals and procedures are overseen by a Joint Working Group (JWG) consisting of independent U.S. and Indian investigators and staff from participating agencies with expertise covering the range of topics to be addressed by the MCHDR program. Scope of the Program The goal of the MCHDR program is to "facilitate collaboration on maternal and children's health and human development research, in part, to contribute to global understanding of the causes of morbidity and mortality in women, particularly mothers, children and adolescents." To address shared women and children's health and developmental research concerns, Indian and U.S. scientists will undertake a coordinated program that will involve participation in collaborative, peer-reviewed research projects, scientific workshops and conferences, research training, and technology transfer. Building on a history of productive biomedical and behavioral research collaboration, this cooperation will be based on mutual benefit, trust, and a shared commitment to the advancement of scientific knowledge and its application to improve health. Specific areas to be addressed within this program include, but are not limited to: o Prevention and treatment of leading causes of maternal, neonatal, and pediatric morbidity and mortality (including toxemia, hemorrhage, sepsis, birth asphyxia and trauma, accidents, diarrhea and other infectious diseases, etc.); o Prevention and treatment of low birth weight and intrauterine growth retardation; o Maternal and child nutrition and the role of micronutrients in healthy child bearing and pediatric and adolescent health and development; o Birth defects, genetic disorders, and developmental research; o Improved understanding of pathophysiology, prevention, and treatment of infectious diseases in women and children, including childhood asthma, acute respiratory tract infections, gastrointestinal infections, reproductive tract infections, malignancies, and HIV/AIDS; o Reproductive health including socio-behavioral aspects, birth practices, and evaluation of new contraceptives; o Traditional systems of medicine and practices that have an important impact on the health and wellbeing of women, children, and adolescents; o Emergency obstetric care for miscarriages and other problems of pregnancy, including severe preeclampsia, hemorrhage, and embolism; o Relationship among maternal nutrition, fetal growth/development, and degenerative diseases in later life; and o Analysis, consensus building, and policy formulation on public health benefits of new approaches to improve maternal and child health. Procedures The MCHDR program will fund supplemental grants to existing NIH-funded projects. Priority will be given to investigative collaborations with U.S. investigators currently funded by NICHD. Awards to U.S. investigators will generally be limited to $50,000 per year in direct costs for up to three years. Applications with budgetary requests exceeding this amount will be reviewed by the U.S. Secretariat on a case-by-case basis for appropriateness. U.S. investigators interested in participation in the MCHDR program should contact the US Secretariat at the address listed below to request submission materials. Please note that applications from U.S. investigators for supplemental funding to existing grants must be submitted by the grantee institution on behalf of the grant's Principal Investigator. All materials regarding participation in the MCHDR program must be submitted to both U.S. and Indian Secretariats. U.S. investigators must send inquiries to the U.S. Secretariat at the address listed below; the Indian collaborator(s) must submit identical materials to the Indian Secretariat at the address listed below. After the initial inquiry has been reviewed by both Secrerariats and agreement reached on proposal responsiveness to program areas listed above, both U.S. and Indian investigators will be provided with instructions for submission of proposals that will be jointly evaluated via an ad hoc review conducted simultaneously by both U.S. and Indian Secretariats. The deadline for the submission of full proposal is July 15, 2003. ICMR- and NICHD-constituted review panels will review all full proposals for scientific merit. Final decisions about funding under the MCHDR program will be made by the JWG of the Indo-U.S. MCHDR program. INQUIRIES For further information, contact: U.S. Secretariat MCHDR Daniel J. Raiten, Ph.D. Office of Prevention Research and International Programs National Institute of Child Health and Human Development National Institutes of Health 6100 Executive Boulevard, Room 4, MSC 7510 Bethesda, MD 20892-7510 Telephone: (301) 435-7568 Email: raitend@mail.nih.gov Indian Secretariat MCHDR N.C. Saxena Deputy Director General Chief, Division of Reproductive Health and Nutrition Indian Council of Medical Research Ansari Nagar New Delhi 110029
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