NEI GUIDELINES FOR DATA MONITORING AND OVERSIGHT OF OBSERVATIONAL STUDIES RELEASE DATE: November 10, 2003 NOTICE: NOT-EY-04-001 National Eye Institute (NEI) ( The National Eye Institute (NEI) has established a system for the appropriate monitoring and oversight of the conduct of observational studies supported by the cooperative agreement mechanism. These guidelines are intended to insure the safety of participants and the integrity of the data. The full text of the guidelines are available on the internet at Please direct any inquiries to Dr. Natalie Kurinij, Director, Epidemiology and Clinical Studies, 301-451-2020,

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