NIDDK REPOSITORIES: AVAILABILITY OF RFP Release Date: April 26, 2002 NOTICE: NOT-DK-02-004 (see also NOT-DK-02-006) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (http://www.niddk.nih.gov) The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has a requirement to set up central NIDDK facilities for archival storage of biosamples and data collected in large, multi-site studies. In addition, there is a need for a central genetic sample facility to serve the needs of new studies by providing uniform high- quality laboratory and archiving services. Central archival repositories will enhance the value of large studies by increasing access to the biosamples and data that have been collected. Investigators seeking to reanalyze biosamples and/or data from NIDDK- funded large studies will be able to direct their inquiries to a single central entity, rather than to numerous laboratories with individual storage and access policies. Thus, when appropriate, researchers will be able to obtain samples and/or data expeditiously and efficiently. Objectives: The repositories will serve three separate functions: 1) Biosample repository - Gathering, storing, and distributing samples from studies. The repository will work with investigators in new and ongoing studies to implement an appropriate labeling, aliquoting and storage system that will facilitate the transfer of the biosamples. In some instances, the repository may be directed to acquire samples from studies already completed. 2) Data repository Consulting with new and ongoing studies to prepare research data for eventual use by others. Working with studies and other contractors to develop sample labeling and information exchange systems. Gathering, storing and distributing the complete, finished datasets associated with archived biosamples from completed studies, and helping researchers carry out simple searches of stored datasets. Creating and maintaining the website for the NIDDK Central Repositories. 3) Genetics repository - Providing support services for genetics studies, including cell line immortalization, DNA extraction and storage. Potential offerors may propose on one or more of the projects. A public pre-solicitation meeting was held on November 28,2001. A transcript of this meeting may be obtained at www.niddk.nih.gov/fund/repository/trnscrpt_1101.pdf. The Request for Proposals, RFP NIH-NIDDK-02-04 will be issued on May 6, 2002 and proposals are due by 3:00 p.m., August 5, 2002. To receive a copy of this RFP, please make your request in writing to Ms. Marlene Mireles, Contract Specialist, 6707 Democracy Boulevard, Suite 772, Bethesda, Maryland 20817, telephone number: 301-594-8831. Telephone requests will not be honored. This NOTICE does not commit the Government to a contract award.


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