Release Date:  April 26, 2002

NOTICE:  NOT-DK-02-004 (see also NOT-DK-02-006)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 

The National Institute of Diabetes and Digestive and Kidney Diseases 
(NIDDK) has a requirement to set up central NIDDK facilities for 
archival storage of biosamples and data collected in large, multi-site 
studies.  In addition, there is a need for a central genetic sample 
facility to serve the needs of new studies by providing uniform high-
quality laboratory and archiving services.  Central archival 
repositories will enhance the value of large studies by increasing 
access to the biosamples and data that have been collected.  
Investigators seeking to reanalyze biosamples and/or data from NIDDK-
funded large studies will be able to direct their inquiries to a single 
central entity, rather than to numerous laboratories with individual 
storage and access policies.  Thus, when appropriate, researchers will 
be able to obtain samples and/or data expeditiously and efficiently.

Objectives:  The repositories will serve three separate functions:

1) Biosample repository - Gathering, storing, and distributing samples 
from studies.  The repository will work with investigators in new 
and ongoing studies to implement an appropriate labeling, aliquoting 
and storage system that will facilitate the transfer of the 
biosamples.  In some instances, the repository may be directed to 
acquire samples from studies already completed.
2) Data repository – Consulting with new and ongoing studies to prepare 
research data for eventual use by others.  Working with studies and 
other contractors to develop sample labeling and information 
exchange systems.  Gathering, storing and distributing the complete, 
finished datasets associated with archived biosamples from completed 
studies, and helping researchers carry out simple searches of stored 
datasets.  Creating and maintaining the website for the NIDDK 
Central Repositories.
3) Genetics repository - Providing support services for genetics 
studies, including cell line immortalization, DNA extraction and 

Potential offerors may propose on one or more of the projects.  A 
public pre-solicitation meeting was held on November 28,2001.  A 
transcript of this meeting may be obtained at
The Request for Proposals, RFP NIH-NIDDK-02-04 will be issued on May 6, 
2002 and proposals are due by 3:00 p.m., August 5, 2002.   To receive a 
copy of this RFP, please make your request in writing to Ms. Marlene 
Mireles, Contract Specialist, 6707 Democracy Boulevard, Suite 772, 
Bethesda, Maryland 20817, telephone number: 301-594-8831.  Telephone 
requests will not be honored.  This NOTICE does not commit the 
Government to a contract award. 

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