Notice of Clarification Relevant to Section IV, Application and Submission Information for PAR-20-045 NIDCR Research Grants for Analyses of Existing Genomics Data (R01 Clinical Trial Not Allowed)

Notice Number: NOT-DE-20-010

Key Dates
Release Date: January 23, 2020

Related Announcements
PAR-20-045

Issued by
National Institute of Dental and Craniofacial Research (NIDCR)

Purpose

The purpose of this notice is to remove the heading, Introduction to Application, where required explanation for the team’s expertise in the analysis of genomics and associated data in the context of dental, oral, and craniofacial biology was articulated. This requirement should be addressed under Research Strategy.

This notice applies to the first due date of June 5th, 2020 and all subsequent standard due dates for non-AIDS applications, and May 7th, 2020 and all subsequent standard due dates for AIDS applications.

The following is detailed information about modifications to the FOA.

Section IV. Application and Submission Information

2. Content and Form of Application Submission

PHS 398 Research Plan

Currently reads:

Introduction to Application:

Applicants are expected to explain why the team possesses sufficient expertise in analysis of genomics and associated data in the context of DOC biology.

Research Strategy:

Applicants must describe and justify proposed research strategy clearly. Justify why the data source is appropriate to answer proposed research question(s). Address quality of the data within proposed dataset(s), including relevant variables and data completeness. Describe and justify clearly if work is proposed to tackle causal mechanism of action of candidate causal genetic variants on onset and progression of DOC disease. Describe and justify clearly proposed approach for validation of analysis results or a newly developed analytic method.

Applicants are expected to articulate why the project is likely to succeed in analyzing proposed existing data resources to enhance DOC research and knowledge of DOC biology.

Should read:

Research Strategy:

Applicants are expected to explain why the team possesses sufficient expertise in analysis of genomics and associated data in the context of dental, oral, and craniofacial biology.

Applicants must describe and justify proposed research strategy clearly. Justify why the data source is appropriate to answer proposed research question(s). Address quality of the data within proposed dataset(s), including relevant variables and data completeness. Describe and justify clearly if work is proposed to tackle causal mechanism of action of candidate causal genetic variants on onset and progression of dental, oral, and craniofacial diseases. Describe and justify clearly proposed approach for validation of analysis results or a newly developed analytic method.

Applicants are expected to articulate why the project is likely to succeed in analyzing proposed existing data resources to enhance dental, oral, and craniofacial research and knowledge of dental, oral, and craniofacial biology.

Inquiries

Please direct all inquiries to:

Lu Wang, Ph.D.
National Institute of Dental and Craniofacial Research
Telephone: 301-594-4846
Email: wanglu@nidcr.nih.gov