NOT-DE-17-007: Revision: Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in PA-15-105 "Novel Biomarkers for the Development of HIV Incidence Assays with Improved Specificity (R01)"

Revision: Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in PA-15-105 "Novel Biomarkers for the Development of HIV Incidence Assays with Improved Specificity (R01)"

Notice Number: NOT-DE-17-007

Key Dates
Release Date: December 8, 2016

Related Announcements
PA-15-105
This notice supersedes NOT-DE-17-003.

Issued by
National Institute of Dental and Craniofacial Research (NIDCR)

Purpose

This Notice is to inform potential applicants that the National Institute of Dental and Craniofacial Research (NIDCR) is participating, effective with the publication of NOT-DE-17-003 on November 23, 2016, , in PAR-15-105 "Novel Biomarkers for the Development of HIV Incidence Assays with Improved Specificity (R01)". NOT-DE-17-003 inconsistently listed the title for this FOA and is being rescinded. This Notice adds information about NIDCR's research objectives.

The following sections of PAR-15-105 were updated with the publication of NOT-DE-17-003 and remain modified to reflect the participation of NIDCR in this Funding Opportunity Announcement (FOA).

Part 1. Overview Information

Components of Participating Organizations

National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Dental and Craniofacial Research (NIDCR)

Catalog of Federal Domestic Assistance (CFDA) Number(s)
93.855, 93.856, 93.121

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

Research Objectives

FOA currently reads:
The objective of this research program is to promote the identification of novel HIV biomarkers that can be used to develop HIV incidence assays or algorithms with improved specificity. Such biomarkers might be based on evolution of specific viral parameters or host responses in the first year after HIV infection. Additionally, method development for utilizing the biomarker(s) to identify incident cases in a highly accurate, cost effective assay will be supported.

The modification of the FOA below introduced in NOT-DE-17-003 remains (modification in italics):
The objective of this research program is to promote the identification of novel HIV biomarkers that can be used to develop HIV incidence assays or algorithms with improved specificity. Such biomarkers might be based on evolution of specific viral parameters or host responses in the first year after HIV infection. Additionally, method development for utilizing the biomarker(s) to identify incident cases in a highly accurate, cost effective assay will be supported.

NIDCR is interested in applications that aim to identify and characterize biomarkers from oral biospecimens, e.g. saliva, oral swabs, that can serve as incidence markers for HIV infection. NIDCR does not support clinical trials through this FOA.

Part 2. Section VII. Agency Contacts

Scientific/Research Contact(s)

Gallya Gannot, DMD, PhD
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-451-5096
Email: gallya.gannot@nih.gov

Financial/Grants Management Contact(s)

Diana Rutberg, MBA
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-594-4798
Email: rutbergd@mail.nih.gov

Inquiries

Please direct all inquiries to:

Gallya Gannot, DMD, PhD
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-451-5096
Email: gallya.gannot@nih.gov