Notice of Intent to Publish a Funding Opportunity Announcement for NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

Key Dates

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National Institute on Deafness and Other Communication Disorders (NIDCD)

The National Institute on Deafness and Other Communication Disorders (NIDCD), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research to support the translation of peer-reviewed and published basic research findings into clinical applications that improve human health in the NIDCD mission areas. 

This Notice of Intent to Publish (NOITP) is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The NOFO is expected to be published in December 2024 with an expected application due date in February 2025.

This NOFO will utilize the R01 activity code. Details of the planned NOFO are provided below.

This NOITP encourages investigators with the appropriate expertise and insights to begin to consider applying to NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional) NOFO. The planned NOFO provides an avenue for basic scientists, clinicians, and clinical scientists to jointly initiate and conduct research projects that translate basic research findings into clinical practice for better human health. Though similar in focus to RFA-DC-22-001, which has expired, this NOFO will not allow renewals or extensions, even if previous funded in response to RFA-DC-22-01, PAR-18-533, PAR-17-184, or PAR-14-009.

The planned NOFO encourages milestone-driven applications that support the translation of peer-reviewed and published basic research findings into clinical applications that improve human health in the NIDCD mission areas. Applications may focus on prevention, diagnostics, therapeutics, medical procedures, and/or behavioral modifications that overcome existing challenges and improve clinical care in the areas of hearing, balance, smell, taste, voice, speech and language. Research conducted under this NOFO is expected to include human subjects, however, in rare occasions, preclinical studies in non-human models are allowed, with prior NIDCD approval, when a subsequent clinical trial is anticipated in the near term. Investigator-initiated low-risk clinical trials addressing the mission and research interests of NIDCD are responsive to this NOFO. NIDCD’s definition of a low-risk clinical trial can be found at https://www.nidcd.nih.gov/research/clinical-studies/researchers-professionals/know-what-is-available. Collaborative translational research between basic scientists and clinicians or clinical scientists is strongly encouraged. Connection to the clinical condition must be clearly established and the outcomes of the proposed work must have the potential for practical clinical impact in the near term. Given the emphasis on translation to clinical practice, early engagement with end users (e.g., practicing clinicians, patients) in real-world environments in which these approaches will be employed is expected. 
 

Funding Information

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 

Inquiries

Please direct all inquiries to:

Kelly King, Au.D., Ph.D.
National Institute on Deafness and Other Communication Disorders (NIDCD)
Telephone: 301-402-3458
Email: kingke@nidcd.nih.gov