NOT-DA-14-004: Notice of Availability of Nicotine Research Cigarettes through NIDA's Drug Supply Program

Notice of Availability of Nicotine Research Cigarettes through NIDA's Drug Supply Program

Notice Number: NOT-DA-14-004

Key Dates
Release Date: January 24, 2014

Issued by
National Institute on Drug Abuse (NIDA)

Purpose

This Notice replaces NOT-DA-13-002 to update the catalog of research cigarettes and ordering guidelines from the NIDA Drug Supply Program.

This Notice communicates the availability and procedures for acquisition of nicotine research cigarettes (NRC) through the NIDA Drug Supply Program (DSP). Information provided in this Notice will help the NIDA DSP and research investigators interested in tobacco research effectively plan for the use of NRCs and for responses to Funding Opportunity Announcements.

Limited quantities of NRCs manufactured under the NIDA DSP are available to research investigators under specified parameters such as nicotine and tar yields ,and type as reduced nicotine (RN), reduced nicotine and menthol (RN-Men), reduced nicotine and high tar (RN-HT), reduced nicotine, high tar and menthol (RN-HT-Men), and conventional nicotine (CN). The NIDA DSP will consider requests for its current inventory of NRCs from researcher investigators funded through the NIH to conduct tobacco science research.

To facilitate planning for either usage of the current inventory of NRCs, or future manufacturing needs, the NIDA DSP requests that research investigators who intend to submit requests for NRCs from the NIDA DSP send an email request with the following information: 1) anticipated total quantity (carton) of each type of NRC needed with their Tobacco Product Master File (TPMF) codes and Type, 2) the requested timeline and amounts for initial receipt, and 3) requested timeline of replenishment of each type of NRC. For those research investigators who have NIDA/NIH grants, they can submit their request according to the NIDA DSP Guidelines for Research Chemicals, Controlled Substances, and Nicotine Research Cigarettes (NRC). For more information, please email NIDANRCSupply@mail.nih.gov

Characteristics of the NRC inventory are described in the following table:

TPMF Code	Type	Specifications Nicotine Yield	Specifications Tar Yield
NRC 100	RN-HV	0.02 0.01	3 1.5
NRC 101	RN-HV-Men	0.02 0.01	3 1.5
NRC 102	RN	0.03 0.01	9 1.5
NRC 103	RN-Men	0.03 0.01	9 1.5
NRC 104	RN-Men	0.04 0.02	13 2
NRC 105	RN-HT-Men	0.04 0.02	13 2
NRC 200	RN	0.07 0.02	9 1.5
NRC 201	RN-Men	0.07 0.02	9 1.5
NRC 300	RN	0.12 0.03	9 1.5
NRC 301	RN-Men	0.12 0.03	9 1.5
NRC 302	RN-HT-Men	0.16 0.03	13 2
NRC 400	RN	0.26 0.06	9 1.5
NRC 401	RN-Men	0.26 0.06	9 1.5
NRC 402	RN-HT	0.33 0.06	13 2
NRC 405	RN-HT-Men	0.4 0.08	13 2
NRC 404	RN-HT	0.6 0.12	13 2
NRC 500	RN-HT	0.7 0.15	13 2
NRC 501	RN-Men	0.6 0.12	9 1.5
NRC 600	CN	0.8 0.15	10.5 1.5
NRC 601	CN-Men	0.8 0.15	10.5 1.5
NRC 602	CN-HT-Men	1.1 0.2	16 2
NRC 700	LTNR-HT	1.6 0.3	16 2
NRC 701	LTNR-Men	1.2 0.2	12 2

*Legend:
RN-HV	Reduced Nicotine-High Ventilation
RN-HV-Men	Reduced Nicotine-High Ventilation Menthol
RN	Reduced Nicotine
RN-Men	Reduced Nicotine-Menthol
RN-HT	Reduced Nicotine-High Tar
RN-HT-Men	Reduced Nicotine-High Tar-Menthol
CN	Conventional Nicotine
CN-Men	Conventional Nicotine-Menthol
CN-HT-Men	Conventional Nicotine-High Tar-Menthol
LTNR-HT	Low Tar/Nicotine Ratio-High Tar
LTNR-Men	Low Tar/Nicotine Ratio-Menthol

Inquiries

Please direct all inquiries to:

Hari H. Singh, PhD/ Phylicia Porter, MPH
National Institute on Drug Abuse (NIDA)
Telephone: 301-435-1310/ 301-435-1692
Email: NIDANRCSupply@mail.nih.gov