Notice Number: NOT-DA-13-037
Release Date: September 16, 2013
National Institute on Drug Abuse (NIDA)
The National Institute on Drug Abuse (NIDA) will solicit proposals from qualified organizations capable of maintaining and expanding the NIDA Center for Genetic Studies. A solicitation will be released through the Federal Business Opportunities website (https://www.fbo.gov). The Request for Proposals (RFP) will be released on or about September 27, 2013 and proposals will be due approximately 45 days thereafter.
Research Initiative Details
In this effort, the contractor will be required to:
(1) Receive de-identified clinical, diagnostic, pedigree structure, environmental exposure information and other phenotypic data along with blood samples or other biospecimens from funded grants and/or contracts supporting research on the genetics of addiction and addiction vulnerability;
(2) Process these data and materials to create databases, serum, DNA, RNA, and cell lines;
(3) Widely distribute all data and materials in the NIDA Human Genetics Initiative to qualified investigators in the scientific community in a cost effective manner;
(4) Maintain storage of data and biomaterials;
(5) As stipulated by NIDA staff, perform microarray typing on pre-existing and/or new de-identified biospecimens;
(6) As stipulated by NIDA staff, perform high-throughput sequencing on pre-existing and/or new de-identified biospecimens for genomic and/or epigenomic analyses;
(7) Support the creation of reprogrammed cellular derivatives, such as induced pluripotent stem cells (iPSCs) to facilitate the molecular and cellular study of brain development and addiction processes;
(8) Create a cyberinfrastructure that enables interoperability and full access to distributed data, software and other information science resources as well as research summaries and outbound links for all addiction related studies available through the NIH database of Genotype and Phenotype (dbGaP) system; and
(9) Faciliate NIDA genetic studies data (both genotype and phenotype) being uploaded into NIH databases such as BioSample, and the dbGaP systems.
Please direct all inquiries to:
Brian H. O’Laughlin
NIDA R&D Contracts Management Branch
Office of Acquisitions, NIDA
National Institutes of Health
6001 Executive Blvd., Room 4211 (MSC 9559)
Bethesda, MD 20892-9559
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