Key Dates
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National Cancer Institute (NCI)
The National Cancer Institute (NCI) intends to issue a UG1 NCI National Clinical Trials Network (NCTN) – Network Integrated Translational Science Centers notice of funding opportunity (NOFO). The NCTN Network Group Integrated Translational Science Centers will provide support for leadership and expertise to facilitate incorporating translational science into NCTN Network Group clinical trials, including the conduct of pilot projects to collect preliminary data. The primary goal of the NCTN is the conduct of multi-center, late-phase, clinical treatment trials (i.e., randomized phase 2 and phase 3 trials) and advanced imaging trials across a broad range of cancers, modalities, and diverse patient populations as part of the NCI's overall clinical research program for adults, adolescents and young adults, and children with cancer. The NCTN also conducts, as necessary, preliminary studies needed for development of definitive trials, especially umbrella/basket trials and rare tumor trials, when an extensive, national patient catchment area is required.
This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications.
The NOFO is expected to be published in Fall 2024 with only one expected application due date in late February 2025.
This Notice encourages investigators with expertise and insights into translational science in oncology to begin to consider applying for this NOFO. The funding provides support for well-defined approaches, policies, and procedures to help incorporate translational science into late phase NCTN trials of new therapies and/or advanced imaging, especially with respect to specific cancers and mechanisms underlining resistance to therapy, and the development and conduct of pilot studies. The funding also provides support for enhancing participation of translational science investigators in NCTN Network Group scientific activities and NCTN Program initiatives.
Funding Information
NCI intends to commit $2 million in FY 2026
Two to three
Application budgets are limited to no more than $850,000 in direct costs per year. The total project period requested may not exceed 6 years.
93.394, 93.395
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Eligible Agencies of the Federal Government
Applications are not being solicited at this time.
Inquiries
Please direct all inquiries to:
Margaret Mooney, M.D.
National Cancer Institute (NCI)
Telephone: 240-276-6006
Email: NCINCTNRFA@mail.nih.gov
and Human Services (HHS)
