Notice of Intent to Publish a Funding Opportunity Announcement for NCI National Clinical Trials Network - Network Group Integrated Translational Science Centers (UG1 Clinical Trial Not Allowed)
Notice Number:
NOT-CA-24-088

Key Dates

Release Date:
July 24, 2024
Estimated Publication Date of Notice of Funding Opportunity :
September 25, 2024
First Estimated Application Due Date:
February 24, 2025
Earliest Estimated Award Date:
March 01, 2026
Earliest Estimated Start Date:
March 01, 2026
Related Announcements

None

Issued by

National Cancer Institute (NCI)

Purpose

The National Cancer Institute (NCI) intends to issue a UG1 NCI National Clinical Trials Network (NCTN) – Network Integrated Translational Science Centers notice of funding opportunity (NOFO). The NCTN Network Group Integrated Translational Science Centers will provide support for leadership and expertise to facilitate incorporating translational science into NCTN Network Group clinical trials, including the conduct of pilot projects to collect preliminary data. The primary goal of the NCTN is the conduct of multi-center, late-phase, clinical treatment trials (i.e., randomized phase 2 and phase 3 trials) and advanced imaging trials across a broad range of cancers, modalities, and diverse patient populations as part of the NCI's overall clinical research program for adults, adolescents and young adults, and children with cancer. The NCTN also conducts, as necessary, preliminary studies needed for development of definitive trials, especially umbrella/basket trials and rare tumor trials, when an extensive, national patient catchment area is required.

This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications.
The NOFO is expected to be published in Fall 2024 with only one expected application due date in late February 2025.
 

Research Initiative Details

This Notice encourages investigators with expertise and insights into translational science in oncology to begin to consider applying for this NOFO. The funding provides support for well-defined approaches, policies, and procedures to help incorporate translational science into late phase NCTN trials of new therapies and/or advanced imaging, especially with respect to specific cancers and mechanisms underlining resistance to therapy, and the development and conduct of pilot studies. The funding also provides support for enhancing participation of translational science investigators in NCTN Network Group scientific activities and NCTN Program initiatives.

Funding Information

Estimated Total Funding

NCI intends to commit $2 million in FY 2026

Expected Number of Awards

Two to three

Estimated Award Ceiling

Application budgets are limited to no more than $850,000 in direct costs per year. The total project period requested may not exceed 6 years.

Primary Assistance Listing Number(s)

93.394, 93.395

Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 

Inquiries

Please direct all inquiries to:

Margaret Mooney, M.D.
National Cancer Institute (NCI)
Telephone: 240-276-6006
Email: [email protected]