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National Cancer Institute (NCI)
The National Cancer Institute (NCI) intends to issue a UG1 NCI National Clinical Trials Network (NCTN) – Network Lead Academic Participating Sites notice of funding opportunity (NOFO). The NCTN Network Lead Academic Participating Sites will provide scientific leadership by helping to develop and conduct clinical trials in association with one or more adult Network Groups and will contribute substantial accrual to clinical trials conducted across the entire NCTN. The primary goal of the NCTN is the conduct of multi-center, late-phase, clinical treatment trials (i.e., randomized phase 2 and phase 3 trials) and advanced imaging trials across a broad range of cancers, modalities, and diverse patient populations as part of the NCI's overall clinical research program for adults, adolescents and young adults, and children with cancer. The NCTN also conducts, as necessary, preliminary studies needed for development of definitive trials, especially umbrella/basket trials and rare tumor trials, when an extensive, national patient catchment area is required.
This Notice of Intent to Publish is being provided to allow sufficient time for applicants to develop strong applications.
The NOFO is expected to be published in Fall 2024 with only one expected application due date in late February 2025.
This Notice encourages investigators who provide scientific expertise and leadership in the development and conduct of NCTN cancer treatment trials and whose institution can provide robust accrual to NCTN trials across the Network, including accrual to rare cancers and accrual from special populations, to begin to consider applying for this NOFO. Among the areas of research encouraged in this initiative are collaboration and participation in NCTN initiatives and mentoring of junior investigators in the full spectrum of NCTN clinical trial activities.
NCI intends to commit $35.1 million in FY 2026
32 to 40
Application budgets are limited to no more than $1.7 in direct costs per year. The total project period requested may not exceed 6 years.
93.394, 93.395
Applications are not being solicited at this time.
Please direct all inquiries to:
Margaret Mooney, M.D.
National Cancer Institute (NCI)
Telephone: 240-276-6006
Email: [email protected]