Notice of Intent to Publish a Funding Opportunity Announcement for Dissemination and Implementation Research in Health (R01)

Notice Number: NOT-CA-16-025

Key Dates
Release Date:   March 7, 2016
Estimated Publication Date of Announcement:  May 2016 
First Estimated Application Due Date:  June 2016 
Earliest Estimated Award Date:  April 2017 
Earliest Estimated Start Date:  April 2017

Related Announcements

Issued by
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Human Genome Research Institute (NHGRI)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute on Minority Health and Health Disparities (NIMHD)
National Center for Complementary and Integrative Health (NCCIH)
Office of Disease Prevention (ODP)
Agency for Healthcare Research and Quality (AHRQ)


The National Cancer Institute (NCI), with other participating NIH Institutes and Centers (ICs), intends to reissue a Funding Opportunity Announcement (FOA) to solicit applications for dissemination and implementation (D&I) research in health.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The FOA is expected to be published in May 2016 with an expected application due date in June 2016.

This FOA will utilize the R01 activity code. Details of the planned FOA are provided below.

Research Initiative Details

The purpose of this Funding Opportunity Announcement (FOA) is to support innovative approaches to identifying, developing, testing, evaluating and/or refining strategies to disseminate and implement evidence-based practices (e.g. behavioral interventions; prevention, early detection, diagnostic, treatment and disease management interventions; quality improvement programs) into public health, clinical practice, and community settings.  Conversely, there is a benefit in understanding circumstances that create a need to “de-implement” or reduce the use of strategies and interventions that are not evidence-based, have been prematurely widely adopted, yield sub-optimal benefits for patients, or are harmful or wasteful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged.

Examples of relevant research directions include but are not limited to:

  • Studies of strategies to implement health promotion, prevention, screening, early detection, and diagnostic interventions, as well as effective treatments, clinical procedures or guidelines into existing care systems.
  • Studies of the implementation of multiple evidence-based practices within community or clinical settings to meet the needs of complex patients and diverse systems of care.
  • Studies of the local adaptation of evidence-based practices in the context of implementation that systematically identify intervention components that surpass or fall short of expected intervention effects.
  • Longitudinal and follow-up studies on the factors that contribute to the sustainability of evidence-based interventions in public health and clinical practice.
  • Studies testing the effectiveness and cost-effectiveness of dissemination or implementation strategies to reduce health disparities and improve quality of care among rural, minority, low literacy and numeracy, and other underserved populations.
  • Studies of the de-implementation of clinical and community practices that are not evidence-based, have been prematurely widely adopted, yield sub-optimal benefits for patients, or are harmful or wasteful.
  • Studies of the relationship of context and local capacity of clinical and community settings to adoption, implementation and sustainability of evidence-based practices.
  • Prospective or retrospective studies of the adoption, implementation and sustainability of health policies and their interaction with programs and contextual factors.
  • Studies of influences on the creation, packaging, transmission and reception of valid health research knowledge.
  • Studies of systems interventions to impact organizational structure, climate, culture, and processes to enable dissemination and implementation of clinical/public health information and effective clinical/public health interventions.
  • Studies that focus on the development and testing of theoretical and evaluation models for D&I processes.
  • Development of D&I relevant outcome and process measures and suitable methodologies for dissemination and implementation approaches. 
  • Studies of the dissemination of varied strategies to promote effective patient and caregiver communication, leading to improved healthcare delivery and outcomes.
  • Studies of the dissemination and implementation of effective and cost-effective strategies for incorporating genomic medicine, sequence-based diagnostics and therapeutics in clinical care.
  • Studies testing the implementation and use of genomic information, family history risk information, and/or pharmacogenetic information for improved diagnosis and treatment.



Please direct all inquiries to:

David Chambers, D.Phil.
National Cancer Institute (NCI)
Telephone: 240-276-5090

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