Clarification of the Scope of Research Projects to be Supported by PAR-11-150 "Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01)"

Notice Number: NOT-CA-13-011

Key Dates
Release Date: July 18, 2013

Related Announcements
PAR-11-150

Issued by
National Cancer Institute (NCI)

Purpose

The purpose of this Notice is to clarify specific requirements and aspects of the scientific scope of Funding Opportunity Announcement (FOA) PAR-11-150, entitled “Quantitative Imaging for Evaluation of Responses to Cancer Therapies (U01),” heretofore referred to as the Quantitative Imaging Network (QIN).

In response to inquiries from prospective applicants, the NCI clarifies the following points pertinent to language in PAR-11-150 that refers to research resources which include, for example, informatics, data archiving, and software tool-sharing requirements.

Therefore, the following text is hereby added to Part 2. Section I. Funding Opportunity Description, 1. Research Objectives, under Specific Goals and Requirements just after the statement "Plans for progressive validation of the components for targeted {of} Phase 1 and 2 trials must also be described."

Resource  Areas. Although the primary research emphasis of this FOA is the development and evaluation of methods to support the prediction and/or evaluation of responses to therapy, expanded development of QIN network-wide research sources are necessary for current and future QIN research sites to conduct this research more effectively. Given the expanding scope of resources needed, the specific purpose of this Notice is to add an opportunity for applications to be focused only on supporting QIN network-wide research resources. Applicants who propose such applications should have prior research experience and capability in prediction and/or evaluation of responses to cancer therapy. They should show how the proposed research resources will support comparisons of the performance of related tools and methods for an array of imaging and/or molecular commercially supported imaging modalities, and/or their adoption in clinical trials.

By way of example only, applications may be focused on one or more of the following research resources:

All tools and methodology must be open source and open access such that they can be implemented by other members of QIN and the scientific community.

It is anticipated that if several such applications are funded, a federated data archive and tool sharing resource will implemented as a Trans-QIN resource.

All other aspects of the FOA remain unchanged.

Inquiries

Please direct all inquiries to:

Robert J. Nordstrom, Ph.D.
Cancer Imaging Program
Division of Cancer Treatment and Diagnosis
National Cancer Institute
Telephone: 240-276-5934
Fax: 240-276-7890
Email: nordstrr@mail.nih.gov

James Deye, Ph.D.
Radiation Research Program
Division of Cancer Treatment and Diagnosis
National Cancer Institute
Telephone: 240-276-5705
Fax: 240-276-5827
Email: deyej@mail.nih.gov

 


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