Rapid Access to Intervention Development (RAID)

Notice Number: NOT-CA-07-018

Key Dates
Release Date: May 18, 2007

Issued by
National Cancer Institute (NCI) , (http://www.nci.nih.gov)

The NATIONAL CANCER INSTITUTE (NCI) is requesting project proposals in response to the Rapid Access to Intervention Development (RAID) Program. The RAID Program will make available to academic investigators, on a competitive basis, the preclinical development contract resources of NCI's Developmental Therapeutics Program (DTP). RAID is not a grant program. Proposed projects that are approved by an external review committee will gain access to the drug development contract resources of the DTP that are managed by DTP staff members. The goal of the RAID Program is the rapid movement of novel molecules and concepts from the laboratory to the clinic for proof-of-principle clinical trials with scientific priority focusing on disproportionate unmet needs such as:

The RAID Program will assist investigators who submit successful project proposals by providing any (or all) of the preclinical development steps that may be obstacles to clinical translation. Possible tasks may include: production; bulk supply; good manufacturing process (GMP) manufacturing; formulation; and toxicology. Suitable agents for RAID will include: small molecules; biologics; and/or vaccines.

There are two receipt dates, February 1 and August 1, for requests for RAID support per year. All RAID proposals are to be filed electronically (i.e., through use of a secure web-based procedure) with the NCI; the window of opportunity for electronic filing will be open starting July 1 ending on the receipt date of August 1. Paper copies of RAID proposals will no longer be accepted via any means of delivery. Each interested investigator must register for a certificate for electronic filing.

For information on the procedures for requesting RAID resources and for electronically filing a RAID proposal, visit the DTP web site at http://dtp.nci.nih.gov/. Inquiries are encouraged and DTP staff members welcome opportunities to clarify issues or to answer questions about the RAID program. Academic investigators may have collaborations with small-business partners and still qualify for RAID funding. Non-profit organizations other than universities may also submit project proposals to RAID. Please note that a maximum of two distinct requests for support per investigator can be submitted for each receipt date.


Inquiries regarding this Notice may be directed to:

Office of Associate Director
Developmental Therapeutics Program
Division of Cancer Treatment and Diagnosis
National Cancer Institute
6130 Executive Boulevard, EPN Suite 8022, MSC 7458
Bethesda, MD 20892-7458
Telephone: 301-496-8720
Fax: 301-402-0831
Email: raid@dtpax2.ncifcrf.gov

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