RELEASE DATE:  August 14, 2003

NOTICE:  NOT-CA-03-036

National Cancer Institute (NCI)

The Cancer Therapy Evaluation Program (CTEP), Division of Cancer 
Treatment and Diagnosis (DCTD) of the National Cancer Institute (NCI) 
is seeking support to systematically test agents in childhood cancer 
pre-clinical models.  The primary objective of this RFP is to identify 
and calibrate a panel of predictive pediatric pre-clinical models to 
inform pediatric oncologists' prioritization of new agents for 
evaluation in children with cancer.  The Contractor will systematically 
test 10-15 agents or combinations of agents per year against a panel of 
pre-clinical models of the childhood cancers that occur most commonly 
in children.  The intended outcome of the project is to improve 
survival for children with cancer by identifying for clinical testing 
the most effective agents from among the universe of oncologic agents 
potentially available for evaluation in children with cancer. The 
detailed Solicitation (RFP: N01-CM-37027-23) will be available on or 
about August 20, 2003 on the Research Contracts Branch, NCI website, 
with a due date for receipt of proposals of October 6, 2003.   The web 
site of the Research Contracts Branch, NCI is: and click Current Request for 
Proposals.  The RFP will include instructions for submission of 
proposals and evaluation criteria.


For further information, contact:

Doris Rosenblatt
Contracting Officer
Treatment, Biology, and Sciences Section, RCB
Executive Plaza South
6120 Executive Blvd.
Rockville, MD 20892-7193
Telephone: 301-496-8620
Fax: 301-402-6699

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