Release Date:  March 5, 2002

NOTICE:   NOT-CA-02-014

National Cancer Institute (NCI)  

The National Institutes of Health (NIH -, National 
Center for Complementary and Alternative Medicine (NCCAM - seeks a Contractor to develop standardized products 
for cranberry (Vaccinium macrocarpon) (1) juice cocktail, (2) concentrate, 
and (3) encapsulated powders, and their matching placebos.  These products 
will be used in NIH-supported research grants.  It is important that the 
cranberry products for NIH-supported research be of a high quality.  The 
NCCAM's plans for research on cranberry include award of (1) this Contract
for development and production of research-grade cranberry products and
placebos and (2) subsequent grants for basic and clinical research on the
role of cranberry in the prevention and treatment of urinary tract 
infections (UTI), other infections, and other conditions for which there 
is credible evidence of efficacy.  
Award of the Contract for cranberry product development is the first 
step in the overall program.  The Contractor shall support the 
preparation, characterization, standardization, and maintenance of a 
supply of research-grade cranberry products and matching placebos with 
concomitant quality control and quality assurance.  The Contractor 
shall provide adequate information about the source, collection, 
storage, processing, extraction and purification process, formulation, 
stability, and safety of the products in order to meet Food and Drug 
Administration requirements for the filing of Investigational New Drug 
applications.  The Contractor shall be responsible for producing, 
labeling, packaging, storing, inventorying and distributing two batches 
of the cranberry products and placebos to the grantees.  Provision of 
products to grantees means that the Contractor shall scale up from 
developing research-grade materials to the manufacture of larger 
quantities of the product.  The detailed Request for Proposal 
Announcement (RFP: N01-AT-21011-64) is available on the web site of the 
Research Contracts and Acquisition Branch, NCI at: with instructions 
for submission of proposals and evaluation criteria.


For further information, contact:

James Carder
Contract Specialist
Phone (301) 435-3776 (No collect calls will be accepted.)
Email address: 
Fax (301) 480-0241. 

Return to Volume Index

Return to NIH Guide Main Index

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.