Release Date:  March 12, 2001

NOTICE:  NOT-AR-01-006


National Institute of Arthritis and Musculoskeletal and Skin Diseases

The National Institute of Arthritis and Musculoskeletal and Skin Diseases 
(NIAMS), National Institutes of Health, is seeking an organization to develop 
a  laboratory using the Food and Drug Administration (FDA) Good Manufacturing 
Practices (GMP)/Current Good Tissue Practice (CGTP) for the production of NIH 
3T3 cells used as feeder cell layers for keratinocyte cultures for cutaneous 
gene therapy applications.  The contractor will be required to: 1) develop 
cell culture techniques for NIH 3T3 cells; 2) establish and operate a 
facility required for the development and production of the NIH 3T3 cells 
within 12 months of contract award; and 3) produce and package for delivery to 
recipients the NIH 3T3 cells.  The activity will require managerial resources 
for the preparation and distribution of the NIH 3T3 cells.

It is anticipated that one cost reimbursement contract award will be made for 
a period of five years beginning on or about September 30, 2001.  The 
solicitation NIH-NIAMS-01-06 will be available electronically on or about 
fifteen days from the date of this notice and may be accessed through the 
Internet at the following address:  Proposals will be due on 
or about May 22, 2001. Offerors are responsible for downloading their own 
copy of the solicitation and amendments and for routinely checking the 
Internet site for any possible solicitation amendments that may be issued by 
the Government.  All responsible sources may submit proposals which will be 
considered by the Government.  The North American Industrial Classification 
System (NAICS) code for this acquisition is 541710.  This advertisement does 
not commit the Government to award a contract.

Inquiries may be directed to:

Elizabeth Shanahan 
Contract Officer
Contracts Management Branch, EP
National Institute of Arthritis and 
Musculoskeletal and Skin Diseases
Natcher Building, Room 5AS13A
45 Center Drive, MSC 6500
Bethesda, Maryland  20892-6500
Telephone: 301-594-2543
FAX: 301-480-5996
Email address:

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