Notice Number: NOT-AI-15-042

Key Dates
Release Date: June 17, 2015

Issued by
National Institute of Allergy and Infectious Diseases (NIAID)

Purpose

The purpose of this Notice is to inform potential applicants of National Institute of Allergy and Infectious Diseases (NIAID's) participation, effective immediately, in the Funding Opportunity Announcement (FOA), PA-15-010, entitled " Spatial Uncertainty: Data, Modeling, and Communication (R01)".

PA-15-010 has been updated in the following ways to reflect NIAID's participation in this FOA.

Part 1. Overview Information

Components of Participating Organizations
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Environmental Health Sciences (NIEHS)

Catalog of Federal Domestic Assistance (CFDA) Number(s): 93.393, 93.399, 93.113, 93.856, 93.855

Part 2. Section I. Funding Opportunity Description

Background

Scope of the FOA

D. Specific Areas of Interests of Participating Institutes/Centers
The National Cancer Institute (NCI) is interested in general methodology of spatial statistical models and visualization tools that are applicable to disease control and prevention especially as related to cancer and cancer patients.

The National Institute of Allergy and Infectious Diseases (NIAID) is interested in the development of spatial and temporal statistical/mathematical models to predict the spread and transmission of infectious diseases such as HIV/AIDS, malaria, tuberculosis, and other emerging and re-emerging infectious diseases. The prediction will be used to guide local prevention efforts to ensure care relevance to the local population. The spread of infectious agent (spore release, infected vector, infected host) exhibits spatial and temporal patterns. Estimates of disease patterns or trends contain a certain degree of uncertainty that makes the identification of the source of exposure and the calculation of the amount of exposure difficult. Bias may be introduced if the uncertainty is ignored or misunderstood. Examples of specific interests to NIAID include:

• Development of statistical methods to analyze outbreak to determine whether there was a spatial pattern in the incubation periods;
• Development of statistical tests to compare the incubation period distributions to determine if there is a significant distance effect;
• Development of mathematical models to study dispersion modeling at finer scales, for example within a building or within the vicinity of the release location;
• Development of methods to evaluate the sensitivity of the methods developed and to identify sources of spatial uncertainty; and
• Development of methods for quantifying spatial uncertainty in identifying core hot spots/cold spots in disease transmission and intervention.

The National Institute of Environmental Health Sciences (NIEHS) is interested in the general methodological issues of spatial uncertainty that are relevant in the research into environmental exposures and the health impacts.

Part 2. Section VII. Agency Contacts

Scientific/Research Contact(s)
Misrak Gezmu, Ph.D. 
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-669-5232
Email: mgezmu@niaid.nih.gov

Financial/Grants Management Contact(s)
Ann Devine
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-669-2988
Email: Ann.Devine@niaid.nih.gov

Inquiries

Please direct all inquiries to:

Misrak Gezmu, Ph.D. 
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-669-5232
Email: mgezmu@niaid.nih.gov