Notice Number: NOT-AI-05-020
Release Date: January 10, 2005
The purpose of the acquisition is to establish a Data Analysis and Coordinating Center (DACC) for the Tri-Service AIDS Clinical Consortium (TACC), hereinafter referred to as the TACC DACC. The TACC is a multi-site, natural history study of HIV infection affecting primarily active duty U.S. military personnel and beneficiaries. The specific objective and scope of the TACC are to address the critical research questions on the natural and treated histories of HIV infection to minimize the adverse effects of HIV on the U.S. military community. The TACC collects medical, laboratory, and epidemiological data from the cohort to facilitate investigations of the biology and epidemiology of HIV transmission and factors affecting disease progression, the effectiveness of therapy, and HIV treatment outcomes. The services of a DACC are being sought to enhance the conduct of the TACC by providing expertise in epidemiology and biostatistical methods that optimize analyses of longitudinal HIV cohort data and fully utilize the network of TACC clinical sites, laboratories and specimen repositories. A sound methodological approach to the measurement of disease incidence, prevalence, and progression, based on currently used or new surrogate markers, shall be necessary in several TACC studies where key events, such as time of HIV seroconversion, are unknown. Additionally, the DACC will provide technical expertise in data collection, data management and quality assurance to produce a valid and reliable database for analyses. The DACC will participate in TACC conference calls, assist in reviews of proposed concepts, and will be expected to play a dynamic role in interacting with the TACC sites to guide the science of HIV research, and in helping to establish priorities and reasonable timelines for study activities, data analyses, and publications. Specifically, the Contractor shall carry out the following functions: 1) Establish and maintain collaborative relationships with the TACC study sites and the TACC Coordinating Team (CT); 2) Provide data cleaning, validation, and quality assurance for existing data and ongoing data collection activities; 3) Establish and maintain data security; 4) Support, train study staff, and facilitate management of cohort study operations; 5) Provide consultation in scientific study design and analytic strategies; 6) Initiate and conduct extensive cutting-edge data analyses for all retrospective, prospective, and collaborative research; 7) Consult in the design and analyses of data from clinical trials conducted within the cohort; 8) Provide data summaries for required scientific reports and presentations; 9) Document all data interactions, cleaning procedures, and analytic programs; and 10) Provide a transition of all data and documentation at the conclusion of the contract. The TACC DACC shall establish and administer efficient, reliable and responsive system for electronic communication among TACC clinical sites, NIAID Project Officer, and the TACC CT and for the collection, management, integration, quality assurance and reporting of study data. Offerors should demonstrate expertise in HIV longitudinal cohort study design, in the implementation and monitoring of longitudinal data collection, in statistical analyses of longitudinal data, in managerial ability to achieve delivery or performance requirements, and in the successful development and implementation of computerized databases and laboratory data management systems.
It is anticipated that one (1) cost-reimbursement, completion type contract will be awarded for a period of five (5) years, beginning approximately November 15, 2005. RFP NIH-NIAID-DAIDS-06-06 will be available electronically on or about January 21, 2005, and may be accessed at http://www.niaid.nih.gov/contract/rfps.htm or http://www.fedbizopps.gov/. Only electronic copies of the solicitation will be available. All information required for the submission of an offer will be contained in the solicitation. Responses to this RFP will be due on/before March 21, 2005.
Any responsible Offeror may submit a proposal that will be considered by the Government, however, this notice does not commit the Government to the award of a contract. No collect calls will be accepted.
Contracting Office Address:
Department of Health and Human Services
National Institutes of Health
National Institute of Allergy and Infectious Diseases
Division of Extramural Activities
Contract Management Program
6700-B Rockledge Drive
Room 3214, MSC 7612
Bethesda, MD 20892-7612
Point of Contact:Barbara Shadrick, Contracting Officer, Phone 301-496-7288, Fax 301-402-0972, Email firstname.lastname@example.org
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
Office of Extramural
National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
Department of Health
and Human Services (HHS)
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