INTER-INSTITUTE PROGRAM FOR THE DEVELOPMENT OF AIDS-RELATED THERAPEUTICS RELEASE DATE: April 4, 2003 NOTICE: NOT-AI-03-022 National Institute of Allergy and Infectious Diseases (NIAID) National Cancer Institute (NCI) Application Receipt Date: June 1, 2003 The Inter-Institute Program for the Development of AIDS-Related Therapeutics (IIP) is co-sponsored by The National Institute of Allergy and Infectious Diseases (NIAID) and National Cancer Institute (NCI). Investigators are invited to submit proposals to this therapeutics development program. IIP is designed to help AIDS research investigators facilitate the pre-clinical development of: 1) therapies for the treatment of HIV disease, AIDS-associated malignancies, opportunistic infections and tuberculosis associated with AIDS, and 2) microbicide-based prevention strategies for HIV. IIP does NOT fund grants. Instead, applications to the program are requests to use IIP drug development resources to conduct specific tasks the applicants themselves are unable to carry out in their efforts to translate basic research findings to applied or clinical practice. Examples of tasks that may be requested include High Throughput Screen (HTS) assay development, evaluation in animal efficacy models, Good Manufacturing Practice (GMP) scale-up synthesis of small molecules and biologics, clinical dosage formulation and manufacturing, and Good Laboratory Practice (GLP) toxicology. Program proposals are solicited twice per year on June 1 and December 1 and reviewed in a competitive manner. The current deadline for receipt of applications is June 1, 2003; prior to that date (no later than May 1, 2003) a Letter of Intent must be submitted to the Inter-Institute Program Coordinator. Further information about this program, including detailed instructions for preparing proposals and the Letter of Intent, can be found at the program web site at http://dtp.nci.nih.gov/docs/dart.html. INQUIRIES IIP Coordinator 6130 Executive Boulevard, Suite 8000 Rockville, MD 20852 T.(301) 496-8720 E-mail: iip@dtpax2.ncifcrf.gov
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