HYPERACCELERATED AWARD/MECHANISMS IN IMMUNOMODULATION TRIALS: EXPANSION OF RFA AI-02-003 TO INCLUDE BIODEFENSE RESEARCH Release Date: July 22, 2002 NOTICE: NOT-AI-02-034 National Institute of Allergy and Infectious Diseases (NIAID) (http://www.niaid.nih.gov/) LETTER OF INTENT RECEIPT DATE: One month prior to application receipt date. APPLICATION RECEIPT DATE: Applications will be accepted MONTHLY on the 9th of each month. PURPOSE OF THIS NOTICE To inform the research community of expanded funds available to conduct investigator-initiated mechanistic studies in clinical trials of vaccines focused on Category A, B and C agents of bioterrorism and emerging/re- emerging infectious diseases (see list of agents at http://www2.niaid.nih.gov/Biodefense/bandc_priority.htm. Specifically, immunological studies that include samples and data from patients enrolled in vaccine trials are sought for evaluation of the underlying immune mechanisms of effective responses or adverse reactions to candidate vaccines. Such information will provide the fundamental understanding needed for development of improved vaccines, and may provide useful surrogate biomarkers of immune responses. As described in the RFA, the parent or core clinical trial must have independent financial support and will NOT receive support under this expanded RFA. Proposed mechanistic studies associated with clinical trials supported by industry are particularly encouraged, but clinical trials supported by any source, public or private, are eligible. Consult the original RFA at https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-02-003.html for additional details and for important information on research objectives and scope, eligible institutions and principal investigators, special requirements, letters of intent, application submission procedures, review and award criteria, and the receipt and review schedule. NIAID maintains comprehensive information on its programs in biodefense and emerging infectious diseases at http://www.niaid.nih.gov/publications/bioterrorism.htm. MECHANISM OF SUPPORT The R01 funding mechanism is used. A greatly accelerated schedule of review and award of applications is used to ensure the ability to fund projects in a timely manner. Thus, highly meritorious applications selected for funding under this RFA will receive their awards thirteen weeks after the application receipt date. Holidays and other circumstances may alter this schedule slightly. FUNDS AVAILABLE For fiscal year 2003, additional funds of $5,000,000 are available for biodefense vaccine studies of immune mechanisms. Although the financial plans of the NIAID provide support for this program, awards pursuant to this RFA are contingent upon the availability of funds and the receipt of a sufficient number of meritorious applications. INQUIRIES Inquiries are strongly encouraged. Opportunities to clarify any issues or questions from potential applicants are welcome. Direct your questions about scientific/research issues to: Kristy Kraemer, Ph.D. Division of Allergy, Immunology and Transplantation National Institute of Allergy and Infectious Diseases National Institutes of Health Room 5124, MSC-7640 6700-B Rockledge Drive Bethesda, MD 20892-7640 (Express Mail: 20817) Phone: 301-496-5598 FAX: 301-402-0175 e-mail: kkraemer@niaid.nih.gov Direct inquiries regarding peer review to: Alexander D. Politis, Ph.D. Center for Scientific Review National Institutes of Health Room 4204, MSC-7812 6701 Rockledge Drive Bethesda, MD 20892-7812 (Express Mail: 20817) Phone: 301-435-1225 FAX: 301-480-4042 E-mail: ap147h@nih.gov Direct inquiries regarding fiscal matters to: Ann White-Devine Division of Extramural Activities National Institute of Allergy and Infectious Diseases National Institutes of Health Room 2118, MSC 7614 6700-B Rockledge Drive Bethesda, MD 20892-7614 Phone: (301) 402-5601 Fax: (301) 480-3780 Email: adevine@niaid.nih.gov
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NIH Funding Opportunities and Notices
Office of Extramural Research (OER) |
National Institutes of Health (NIH) 9000 Rockville Pike Bethesda, Maryland 20892 |
Department of Health and Human Services (HHS) |
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