Notice of Intent to Publish a Notice of Funding Opportunity for Coordination Center for the Alzheimer’s Disease Sequencing Project Consortium (U01 Clinical Trial Not Allowed)

Key Dates

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National Institute on Aging (NIA)

The National Institute on Aging (NIA) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to invite applications for the Coordination Center for the Alzheimer’s Disease Sequencing Project (ADSP) Consortium.

The concept for this NOFO was approved by the National Advisory Council on Aging in September 2023 under the title “Limited Competition: Renewal of, and Revisions to, the Alzheimer’s Disease Genetics Consortium (ADGC).” Potential applicants should note that eligibility has been expanded, and the NOFO will be issued under open competition. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The NOFO is expected to be published in November 2024 with an expected application due date in February 2025.

This NOFO will utilize the U01 activity code. Details of the planned NOFO are provided below.

The Coordination Center for the Alzheimer’s Disease Sequencing Project Consortium (hereafter referred to as the ADSP Consortium Coordination Center) will be responsible for the administration and coordination of the ADSP consortium. The ADSP consortium includes the following major components:

• Diverse cohort studies
• Genetic analysis projects
• Phenotype harmonization consortium
• Functional genomics consortium
• Artificial intelligence and machine learning consortium
• Infrastructure supporting data collection and sharing

The ADSP Consortium Coordination Center will lead and manage cross-consortium functions, including effective communication, collaboration, outreach, dissemination, training, and coordination across the components of the ADSP. The Center will be the main conduit for collaboration with the NIH- and NIA-funded relevant programs and the global AD genetics research community. The Center must have a clear strategy for building trust, emphasizing a culture of collaboration and responsibility, and aligning all the stakeholders to the overall mission of the ADSP.

The overall goal of the ADSP Consortium Coordination Center is to integrate the efforts of all the ADSP projects, and, through innovation, to promote a research environment that facilitates synergy, collaboration, and communication among ADSP investigators. Through the development and administration of the ADSP website and other communication channels, the ADSP Consortium Coordination Center will serve as the community-wide resource and externally facing point of access to the resources and products developed by the ADSP. The ADSP Consortium Coordination Center will also be responsible for publicizing information related to the ADSP to the broader research community.

Applications are sought from multidisciplinary teams with national and global expertise in genetics of AD/ADRD, organizational management, team science, communications, outreach and engagement, training, and website development. The team should demonstrate the capability to support a wide range of activities and take a flexible, adaptive approach to coordinating the ADSP consortium. 

Funding Information

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 

Inquiries

Please direct all inquiries to:

Damali Martin, Ph.D., MPH
Division of Neuroscience
National Institute on Aging (NIA)
Email: martinda@mail.nih.gov