March 8, 2022
PAR-22-072 - Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed)
National Institute on Aging (NIA)
This Notice informs potential applicants that the National Institute on Aging (NIA) is participating, effective immediately, in Funding Opportunity Announcement (FOA) PAR-22-072, "Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed)."
The following sections of PAR-22-072 have been modified:
Part 1. Overview Information
Components of Participating Organizations
Currently Reads:
National Institute on Minority Health and Health Disparities (NIMHD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Cancer Institute (NCI)
National Eye Institute (NEI)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)
Office of Behavioral and Social Sciences Research (OBSSR)
Sexual and Gender Minority Research Office (SGMRO)
Modified to Read (changes shown in bold italics):
National Institute on Minority Health and Health Disparities (NIMHD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Cancer Institute (NCI)
National Eye Institute (NEI)
National Institute on Aging (NIA)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)
Office of Behavioral and Social Sciences Research (OBSSR)
Sexual and Gender Minority Research Office (SGMRO)
Assistance Listing Number(s)
Currently Reads:
93.307, 93.393, 93.395, 93.396, 93.121, 93.113, 93.242
Modified to Read (changes shown in bold italics):
93.307, 93.393, 93.395, 93.396, 93.121, 93.113, 93.242, 93.866
Part 2. Full Text of Announcement
Section I. Funding Opportunity Description
This section was modified to add:
National Institute on Aging (NIA)
NIA supports research to understand health differences and health inequities associated with race, ethnicity, gender, environment, socioeconomic status (SES), geography, access, and sociocultural factors over the life course and their impact on aging processes, and aging-relevant outcomes including Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD). The goals of this initiative are to (1) identify the environmental, social, cultural, and behavioral factors that drive disparities in health, well-being, healthcare, and mortality; and (2) develop strategies to reduce or eliminate those disparities and promote active life expectancy and improve the health status of diverse midlife and older adults. NIA's Health Disparities Research Framework reflects levels of analysis researchers might consider across each of the four domains, refines the causal pathways, and further refines potentially adaptable targets for interventions. Additionally, the framework reflects priorities and investments made in this important aging research area. The framework could also facilitate researchers identifying relevant expertise needed to expand their team and ultimately accomplish the proposed study’s goals and objectives.
NIA’s interests in PAR-22-072, “Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs” include, but are not limited to, development of, or enhancements to, measures or methods for assessing constructs related to minority health and health disparities, such as the following:
- Methods that capture composite and cumulative exposure to adversity, structural racism, and discrimination.
- Measurement of protective (and resilience) factors that contribute to (or buffer against) health disparities in AD/ADRD outcomes, at both the individual (e.g., personality traits, psychological resources, behavioral skills) and sociocultural levels (e.g., interpersonal, community, societal).
- Analytic methods to generate causal evidence from observational and non-clinical studies to inform the prevention and mitigation of health disparities in AD/ADRD and increase confidence in observational results as evidence of treatment efficacy or effectiveness in populations underrepresented in AD/ADRD research.
- Development of analytical tools to dynamically assess health and exposure to risk and protective factors across multiple timescales, including mobile technology-based measures that capture lived experiences in “real time,” without imposing undue burden, particularly for populations that experience health disparities.
- Development of analytical tools and methods to promote and support research on the impact of social factors on molecular, cellular, genetic, and physiological mechanisms underlying disparate outcomes in aging and age-related pathologies, particularly for populations that experience health disparities.
- Development of approaches that integrate qualitative and quantitative data collection methods and measures of diverse environmental factors (chemical, physical, built, etc.) with social and behavioral factors associated with aging and age-related neuro-pathologies, including AD/ADRD.
- Development and use of methods for integrating social and behavioral data with molecular, cellular, genomic, other -omic and biological data in epidemiological studies of aging and age-related neuro-pathologies, including AD/ADRD.
- Methods to harmonize measures and conduct analyses using longitudinal cohort studies with heterogenous representation of individuals across different health disparities populations using NIA's Health Disparities Research Framework (i.e., across levels of analysis).
Section VII. Agency Contacts
This section was modified to add:
Scientific/Research Contact(s)
Frank Bandiera, Ph.D.
Division of Behavioral & Social Research (DBSR)
National Institute on Aging (NIA)
Phone: 301-402-7629
Email: frank.bandiera@nih.gov
Financial/Grants Management Contact(s)
Ryan Blakeney
National Institute on Aging (NIA)
Telephone: 301-451-9802
Email: blakeneyr@mail.nih.gov
Frank Bandiera, Ph.D.
Division of Behavioral & Social Research (DBSR)
National Institute on Aging (NIA)
Phone: 301-402-7629
Email: frank.bandiera@nih.gov
and Human Services (HHS)
