SILVIO O. CONTE RESEARCH CENTERS: MODIFICATIONS TO CURRENT PROGRAM ANNOUNCEMENTS Release Date: August 3, 1999 National Institute of Mental Health This is to cite several important changes to the program announcements for Silvio O. Conte Centers for Neuroscience Research (CCNR) (PAR-98-057, http://grants.nih.gov/grants/guide/pa-files/PAR-98-057.html) and Silvio O. Conte Centers for the Neuroscience of Mental Disorders (CCNMD) (PAR-98-058, http://grants.nih.gov/grants/guide/pa-files/PAR-98-058.html). The revisions will be effective with the Application Receipt Date of October 20, 1999. Modified provisions of these two announcements are as follows: 1. Mechanism of Support: Direct costs are limited to $1.5 million in any one year, this limit applies to new grants, their non-competitive continuations, and any subsequent competitive renewals. (This limit does not apply to previously awarded CCNRs or CCNMDs.) Since the best scientific talent and resources are expected to be brought to bear on questions posed in each center, and since these are often not available at one institution, projects constituting a given center may be based at a variety of institutions. In an effort to allow for such multi-institutional involvement, for the purposes of this program announcement, Facility and Administrative costs for such consortial and contractual arrangements will not be counted against the $1.5 million limit to direct costs (but these costs should be delineated as instructed in form PHS 398 [rev. 4/98]). Competitive supplements will not be considered for these center grants. It is anticipated that individual projects, which are developed as outgrowths of a center grant, will seek independent funding through mechanisms such as research project grants (R01 mechanism). 2. Activities Supported: a. The section entitled Essential Scientific Expertise is no longer active, but it is replaced by: Although it is expected that novel findings and alternative paths of inquiry that arise from CCNR/CCNMD-supported research may be pursued with CCNR/CCNMD funds, categorical budgets for unspecified pilot projects may not be made. b. The following section is added: Sharing Data, Biological Material Resources, and Tools Public Health Service (PHS) policy requires that investigators make unique research resources readily available to qualified individuals within the scientific community for research purposes following publication (PHS Grants Policy Statement in the July 12, 1996 issue of the NIH Guide to Grants and Contracts). CCNRs/CCNMDs marshal the very best researchers and resources for investigating neuroscience, and novel data, materials and tools, which can be difficult to develop under smaller mechanisms, are often the result. Therefore, the NIMH requires applicants to develop detailed plans for the dissemination of data and materials generated through the center. (It should be noted that the cost of developing such resources for distribution and the cost of distributing them may be charged to those requesting them.) The plan will be considered part of the scientific methodology for carrying out the research and, as such, the adequacy of the plan will be considered by NIMH staff in determining whether the grant should be awarded. The initial review group will comment on the proposed plan for sharing and data access. The sharing plan as approved, after negotiation with the applicant when necessary, will be a condition of the award. 3. Review Criteria: The following review criterion will also be used: o Appropriateness of plans for the sharing of data, research tools, and biological materials. No other aspects of these two program announcements are changed. INQUIRIES For information regarding these or other aspects of these two announcements, contact: Michael F. Huerta, Ph.D. Division of Neuroscience and Basic Behavioral Science National Institute of Mental Health 6001 Executive Blvd., Room 7196 MSC 9645 Bethesda, MD 20892-9645 Telephone: (301) 443-3563 FAX: (301) 443-1731 Email: mhuerta@helix.nih.gov

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