SBIR and STTR Success Stories
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SBIR/STTR Program Successes
Brief profiles of companies that have utilized the programs and effectively commercialized technologies developed under SBIR/STTR are shown below.
Click Here to submit your company's success story to NIH for inclusion below. Once reviewed, the information will be added to this list. Submissions of items unrelated to the SBIR/STTR programs will not be accepted. The company name and project title for each Success Story are shown below. (Note: The current sort field is shown in red. Click on column header links to re-sort.)
|
Company
|
Project Title
|
Keywords
|
City |
State
|
| Targeting Systems |
NOVEL APPROACH FOR TARGETED GENE DELIVERY TO THE LIVER |
High throughput screening, Transfection, Protein delivery, siRNA delivery/screening, Luciferase assays/vectors, Lentiviral vectors, Stem cell tracking, Stem cell transfections
|
Santee |
CA |
| Transonic Systems, Inc. |
A Flowmeter with Telemetry for Chronic Animal Studies |
Wireless, Transit-Time, Flow, Ultrasound, Bluetooth, Telemetry, Flowmeter, Manufacturing
|
Ithaca |
NY |
| Cleveland Medical Devices Inc. (CleveMed) |
A New Device For Untethered Home Sleep Studies; Intelligent Quantitative CPCP for OSA Therapy; Pre-Operatiave PSG Assessment of Caradiac Surgery InPatients |
Home sleep testing, Sleep disorders, Ambulatory monitoring, Wireless, Polysomnography
|
Cleveland |
OH |
| PortaScience, Inc. |
A Simple Point-of-Care White Blood Cell Count Test |
white blood cell, chemotherapy, mastitis, diagnostic, point-of-care, portable
|
Moorestown |
NJ |
| Pro-Change Behavior Systems, Inc. |
A Stress Management Expert System for Cancer Prevention |
stress management, Transtheoretical Model, Stage of Change, Population Intervention, Tailored Communications
|
West Kingston |
RI |
| Signum Biosciences |
A Topical Non Steroidal Anti-inflammatory for Rosacea |
rosacea, isoprenylcysteine, toll-like receptor, g-protein, anti-inflammatory, topical
|
Monmouth Junction |
NJ |
| Quantum Simulations, Inc. |
Accessible Artificial Intelligence Tutoring Software |
chemistry, education, artificial intelligence, software, tutor, science, blind, visually impaired
|
Murrysville |
PA |
| Simbex |
ActiveStep Fall Prevention Training System |
Fall prevention, Fall-risk assessment, Falls in the elderly, Task specific training, Neuromuscular programming, Dynamic gait training, Fall recovery
|
Lebanon |
NH |
| Vivalog Technologies |
An Application Server for Biomedical Content Management |
content management, radiology teaching files, medical image repository, PACS, enterprise software
|
Seattle |
WA |
| Cyma |
An Easy-to-Use System for Ambulatory Activity Evaluation |
walk, physical activity, ambulatory monitoring, pedometer, StepWatch, SAM, step, instrument
|
Seattle |
WA |
| Concordant Rater Systems |
An Interactive Computer Interview for Mania to Enhance Human Rater Performance |
CNS outcomes, Rater Reliability, Clinical Trials, Site Monitoring, Computerized Adaptive Tes, Mental Health, Bipolar Disorder
|
Boston |
MA |
| Advanced Brain Monitoring, Inc. |
Apnea Risk Evaluation System |
sleep apnea, in-home monitoring, pulse-oximetry, sleep disorders, apnea risk questionnaire
|
Carlsbad |
CA |
| Illumina, Inc. |
Automated DNA Synthesizer Using Tilted Plate Technology |
DNA synthesis, automated synthesizer, SNP analysis, genotyping
|
San Diego |
CA |
| Audiology Incorporated |
Automated Hearing Tests |
hearing test, pure-tone audiometry, speech recognition, speech audiometry, earphone, audiology
|
Arden Hills |
MN |
| Speech Technology & Applied Research Corp. |
Automatic Pronunciation Screening Test |
intelligibility, understandability, pronunciation, linguistics, non-native speaker, English, expert system
|
Bedford |
MA |
| Stereology Resource Center |
Automatic Stereology of Biological Tissue Using 3-D VCS |
stereology, VCS, automatic, cell counting
|
Chester |
MD |
| Biopsy Sciences |
Biodegradable Sealant for Biopsy Tract in Soft Tissue |
BioSEAL, CT guided lung biopsy, hydrogel, pneumothorax, FNA
|
Clearwater |
FL |
| Menssana Research, Inc |
Breath tests for detection of disease |
breath, volatile, heart transplant, lung cancer, breast cancer, tuberculosis
|
Fort Lee |
NJ |
| Behavior Therapy Associates LLP |
Brief intervention for alcoholism via computer software |
alcohol problems, brief intervention, computer intervention, program evaluation
|
Albuquerque |
NM |
| Avedro, Inc. |
Commercialization of Microwave Thermokeratoplasty |
Eye, Vision, Ophthalmology, Refractive, Cornea, Myopia, Microwave, Keratoplasty
|
Waltham |
MA |
| Decision Systems |
COMMUNITY VOICE MAIL FOR ROUTINE AND DISASTER SERVICES |
teleminder, communications, disaster relief, computer system
|
Los Alamos |
CA |
| Illumina, Inc. |
Decoding Randomly- Assembled DNA Arrays |
decoding, bead, random, oligonucleotide, fluorescence, microarray, snp genotyping, gene expression
|
San Diego |
CA |
| Evening Star Productions |
DEVELOPING VIDEO AND PRINT LIBRARY OF LIFE CARE PROGRAMS |
health care, life skills, nutrition and diet, exercise and fitness, legal and financial , video series
|
Akron |
OH |
| NimbleGen Systems, Inc. |
Development of a Maskless Array Synthesizer |
microarray, MAS, ChIP chip, CGH, Expression, Manufacture
|
Madison |
WI |
| Sierra Scientific Instruments, Inc. |
Development of a Motility Visualization System |
Manometry, Motility, High-resolution, Gastroenterology, Esophagus, Stomach, Duodenum, Anorectum
|
Los Angeles |
CA |
| Selexys Pharmaceuticals Corporation |
Development of an Anti-PSGL-1 Antibody to Treat Crohn’s Disease |
inflammation, PSGL-1, antibodies, P-selectin, adhesion, Crohn's Disease
|
Oklahoma City |
OK |
| CFD Research Corporation |
Development of Improved Hemodialysis Catheter Designs |
Catheter, hemodialysis, access recirculation, suction pressure, hemolysis
|
Huntsville |
AL |
| TissueTech, Inc. |
Development of PROKERA® Sutureless Amniotic Membrane Graft |
Amniotic Membrane, Ocular Surface Reconstruc, Wound Repair, Wound Healing, Eye Surgery, Corneal Defects, Chemical Burns, SJS-TEN
|
Miami |
FL |
| TissueTech, Inc. |
Development of Sutureless Amniotic Membrane Graft (AmnioLens) |
amniotic membrane, ocular surface, wound repair, wound healing, eye surgery, corneal defects, chemical burns, Stevens-Johnson Syndrome
|
Miami |
FL |
| Lpath, Inc. |
Development of therapeutic antibodies for cancer and age-related macular degeneration |
antibodies as drugs, cancer, AMD, bioactive lipid targets, sphingosine-1-phosphate, LPA, Immune-Y2 process, ASONEP
|
San Diego |
CA |
| ECI Biotech |
Diagnostic Tool for the Point-of-Care Detection of Infection in Chronic Wounds |
Wound Care, Diagnostic, Bio-burden, Pathogen, Healing, critical colonization, sensor, point of care (PoC)
|
Worcester |
MA |
| Intelligent Optical Systems |
Distributed, sensitive chemical and biochemical sensors and sensor networks. |
Fiber, Sensors, Distributed, Specific, Biofilms, Real-time, Adaptive, Network
|
Torrance |
CA |
| Clinical Tools, Inc. |
Education on Opiate Addiction and Treatment |
Buprenorphine treatment, opioid dependence, buprenorphine training, Data 2000 waiver, ffice-based opioid treatm, prescription opioid misus
|
Chapel Hill |
NC |
| Vida Health Communications, Inc. |
Fetal Alcohol Syndrome - Prevention, Diagnosis, Treatment: A Clinical Guide for Obstetric and Pediatric Providers |
FAS, Prenatal Alcohol Exposure, Obstetrician education, Pediatrician education, Birth Defects, Alcohol-Related defects, FAS Diagnosis, FAS Treatment
|
Cambridge |
MA |
| Chadwick Optical, Inc. |
Field Expansion Prism Glasses for Homonymous Hemianopia |
hemianopia, hemianopsia, quadranopia, quadranopsia, visual field loss, peripheral field loss, Peli Lens, Peli Prism
|
White River Jct. |
VT |
| Transonic Systems, Inc. |
Flow Measurement at Dialysis Access Salvage |
Blood, Dilution, Hemodialysis, Angioplasty, Access Flow, Stenosis, PTFE Graft, Fistulae
|
Ithaca |
NY |
| INDOOR Biotechnologies Inc |
Fluorescent multiplex array for indoor allergens |
allergen, microarray, exposure assessment, asthma, indoor allergens
|
Charlottesville |
VA |
| Samuels & Associates |
Food BEAMS: Food and Beverage Environmental Assessment and Monitoring System |
Competitive foods, Nutrition, Policy Adherence, Data Collection, Policy Monitoring, Schools, Health
|
Oakland |
CA |
| Simbex |
Head Impact Recording Technology for Field Applications |
Brain injury, Concussion, Helmet, HIT System, Head impact, Biomechanics, Telemetry, MTBI
|
Lebanon |
NH |
| Physical Sciences Inc. |
High performance multimode adaptive optics retinal imaging |
Adaptive Optics, Retina, SLO, OCT, Ophthalmic, Cellular resolution, retinal disease
|
Andover |
MA |
| Genomics USA |
HLA Chip Product for FDA 510 (k) Approval |
Microarray Technology, HLA Genotyping, FDA 510 (k) Approval, Raw Sample Genotyping
|
Hoffman Estates |
IL |
| Planning Systems Incorporated |
Hybrid Adaptive Beamformer (HAB) |
array, speech intelligibility, microphone, speech in noise, microphone, beamformer
|
Reston |
VA |
| MIDI, Inc. |
Identification of bacteria direct from blood culture |
Fatty acid analysis, Bacterial identification, Gas chromatography, Sample preparation, Sensitivity, Speed of identification
|
Newark |
DE |
| SAM Technology, Inc. |
IMAGE VUE™ Neurophysiological and Neuroanatomical Visualization and Source Localization Software |
medical imaging, human brain, epilepsy, seizure localization, EEG, MRI, 3-D graphics
|
San Francisco |
CA |
| SurModics, Inc. |
IMPROVED BIOCOMPATIBILITY OF CONTACT LENSES |
Surface modification, Immobilization chemistry, Medical device coatings, Hemocompatibility, Cell encapsulation, Drug-eluting coatings, DNA immobilization, Photoactivation
|
Eden Prairie |
MN |
| EKOS Corporation |
In vivo evaluation of ultrasound enhanced lysis. |
Ischemic Stroke, PAO, Infusion catheters, flow sensor, therapeutic ultrasound, manufacturing
|
Bothell |
WA |
| Organix, Inc. |
Indole Analogs as Novel Treatments for OCD |
serotonin, obesity, 5-HT2C receptor, OCD
|
Woburn |
MA |
| Synabridge Corporation |
Instrument for Glaucoma Early Detection and Monitoring |
VEP, Glaucoma , neural, clinical, diagnosis, screening, electrophysiology, icVEP
|
Raritan |
NJ |
| dbaza, inc. |
INTERACTIVE LEARNING FOR CHILDREN WITH DIABETES |
diabetes education, interactive learning, children with diabetes, pediatric diabetes care, diabetes self-management, CD-ROM
|
Pittsburgh |
PA |
| Morphonix™ |
Journey into the Brain |
CD-ROM, Neuroscience, Education, Multimedia, Computer Game
|
San Rafael |
CA |
| Reaction Biology Corp |
Kinome Drug BioAssay Platform |
kinase, assay, P33, kinome, radiolabeled, radioisotope, hotspot
|
Malvern |
PA |
| The Degge Group, Ltd. |
LEVELS OF LEARNING ABOUT CANCER BY PEDIATRIC PATIENTS |
leukemia, child, cancer, education, interactive, multimedia, CD-ROM, pediatric
|
Arlington |
VA |
| Turbo Wheelchair Co., Inc. |
Lightweight Durable Wheelchair from Engineering Resin |
wheelchair, MRI wheelchair, mobility for seniors, plastic wheelchair
|
Beaufort |
SC |
| iVisit, LLC |
LookTel (formerly SeeStar/SeeScan) |
blind, visually impaired, mobile app, phone accessibility, object recognition, OCR, text reader, video conferencing
|
Santa Monica |
CA |
| SAM Technology, Inc. |
MANSCAN® Human Brain Function Research System |
human brain function, EEG, evoked potential, MRI, digital signal processing, pattern recognition, bioamplifiers, 3D visualization
|
San Francisco |
CA |
| BioSciCon, Inc. |
MarkPap(r) Technology for Cervical Cancer Screening |
MarkPap test, Cervical cancer, Acid phosphatase, Pap test, Cancer biomarkers, Pap smear, Liquid-based Pap, Cancer screening
|
Rockville |
MD |
| Xilas Medical, Inc. |
Medical devices that prevent the occurrence of foot ulcers and amputations in people with diabetes |
diabetes, diabetic foot ulcer, amputations, friction, dermal thermometer, early warning tool, GlideSoft, TempTouch
|
San Antonio |
TX |
| Optiva Corporation |
MEDICINE AND DENTIFRICE DISPENSING SONIC BRUSH, SONIC TOOTHBRUSH |
SONICARE, SONIC, Power Toothbrush, Cleans Beyond the Bristle
|
Snoqualmie |
WA |
| Reaction Biology Corp |
Methyltransferase Drug Discovery |
tritium, 3h, assay, methyltransferase, epigenetic, drug discovery
|
Malvern |
PA |
| Xoran Technologies Inc. |
MiniCAT™ |
MiniCAT, i-CAT, 3D x-ray, Computed Tomography (CT), CT scanner, Temporal Bone CT, Skull-Base CT
|
Ann Arbor |
MI |
| IQ Engines, Inc. |
Mobile Search for the Visually Impaired |
Image Recognition, Object Recognition, Mobile Visual Search, Computer Vision, Crowdsourcing, API, SDK
|
Berkeley |
CA |
| Celadon Laboratories Inc |
Multi-Method Software Platform for Primer and Probe Design |
oligonucleotide, assay design, PCR, SNPs, primers, probes, genomics, bioinformatics
|
Hyattsville |
MD |
| Platypus Technologies, LLC |
Nanostructured substrates for cell assays |
cell migration, cell invasion, motility, drug screening, metastasis, wound healing, tissue repair
|
Madison |
WI |
| MBF Bioscience |
Neurolucida, AutoNeuron, Stereo Investigator, NeuroInformatica, 3D Virtual Slice |
stereology, morphometry, automated analysis, digital image archive, neuron reconstruction
|
Williston |
VT |
| Telesage, Inc. |
NEW AUTOMATED TELEPHONE TECHNOLOGY FOR MENTAL HEALTH |
Patient-Reported Outcomes, IVR, CAT, Mental Health, Substance Abuse, Interactive Voice, Computerized Adaptive, IRT
|
Chapel Hill |
NC |
| CasterShoX |
Noise Attenuation Tech to Prevent Hearing Loss |
Noise Attentuation, Shock Absorption, Noise Induced Hearing Los, Compact, manufacturing
|
Canton |
MI |
| ARISIL, Inc. |
Non-Surgical Device for Treatment of Middle Ear Effusion |
EarPopper, otitis media, middle-ear effusion, eustachian tube, autoinsufflation, Politzer method, manufacturing
|
Brooklyn |
NY |
| Insight NeuroImaging Systems, LLC (INSL) |
Noninvasive Devices for fMRI Studies in Mental Illness |
imaging conscious animals, functional MRI, radiofrequency electronic, mental illness, drug discovery, drug addiction, epilepsy
|
Worcester |
MA |
| KeraMed Inc. |
Novel Keratoprosthesis Designs and Implantation Methods / A robotic device to faciliate corneal transplantation and other corneal surgeries |
artificial cornea, cornea surgery, cornea blindness, robotic surgery
|
Sunnyvale |
CA |
| AmberGen Incorporated |
Novel Proteomic Arrays of In Vitro Expressed Proteins for Autoimmune Disease |
Autoimmune, Autoantibody, Autoantigen, Diagnostics, Proteomics, Protein Expression, Microarray, Biomarker
|
Watertown |
MA |
| Talisman Limited |
Paperless Quality Donor System with Decision Making |
CASI, AVT-CASI , automated interviewing, blood donors, error reduction , honesty, staff satisfaction, donor satisfaction
|
Vienna |
VA |
| Systems Technolgy, Inc. |
PC Based Driving Simulator for Training and Assessment |
Driving Simulator, Driver Assessment, Driver Training, Driver Rehabilitation, Drug Testing
|
Hawthorne |
CA |
| Clever Sys. Inc. |
PhenoScan Series |
digital video, lab animal, behaviors, automated analysis
|
Vienna |
VA |
| Echelon Biosciences Inc |
Phosphoinositide 3-Kinase Assays in Cancer Diagnosis |
Phosphoinositide 3-Kinase, PI 3-K, PI(3,4,5)P3, PI 3-Kinase, PI3K, Echelon
|
Salt Lake City |
UT |
| Physical Sciences Inc. |
Portable Line Scanning Laser Ophthalmoscope |
ophthalmic, eye disease, OCT, laser, confocal, retina
|
Andover |
MA |
| I.S. Grupe, Inc. |
Portable Patient Record |
patient record, medical information, electronic storage, portable
|
Westmont |
IL |
| OncoMetrics*, Inc. |
Precise breast cancer staging with an expert system |
breast cancer, dormancy, surgery, angiogenesis, mammography, racial difference , bimodal relapse, chemotherapy
|
Trumbull |
CT |
| OncoMetrics, Inc. |
Precise breast cancer staging with an expert system |
angiogenesis, breast cancer, surgery, dormancy
|
Trumbull |
CT |
| Leo Lens Technology |
Printing of Digitized Image of Iris for Prosthetic Lens |
Digitized Iris Image, Inkjet printing, Prosthetic lens, Antimicrobial, Contact lens, Silicone Hydrogel, Lens dryness, Friction reduction
|
San Diego |
CA |
| Physical Sciences Inc. |
Process Endpoint Monitor for Lyophilized Biologics for Cancer Treatment |
Lyophilization, Freeze-Drying, TDLAS, Mass Flow Rate, Primary Drying Endpoint, Secondary Drying Endpoint
|
Andover |
MA |
| Vecna Technologies |
QC PathFinder: Signal-Based Analysis of Clinical Microbiology |
healthcare acquired infec, antimicrobial stewardship, antimicrobial resistance, infection control, nosocomial, infection surveillance, infection prevention
|
Greenbelt |
MD |
| Illumina, Inc. |
Randomly Ordered Arrays for SNP Genotyping |
polymorphism, SNP, genotyping, genetics, oligonucleotide, fiberoptic, array, multiplex
|
San Diego |
CA |
| DeltaNu, LLC |
RAPID DETECTION OF PRE-AND NEONATAL METABOLIC DISORDERS |
SERS, Raman, Medical Device, Point of Care, Nanotechnology, Miniature Raman, Laramie, Wyoming
|
Laramie |
WY |
| LigoCyte Pharmaceuticals |
Rational Design of Adhesion Blocking Anti-Inflammatories |
chronic inflammation, antibody, adhesion, pulmonary
|
Bozeman |
MT |
| Hawaii Biotech, Inc. |
Recombinant Vaccine Development and Commercialization |
vaccine, recombinant, West Nile, malaria, influenza, dengue
|
Aiea |
HI |
| MicroTransponder Inc. |
SAINT wireless neurostimulation device |
tinnitus, urinary incontinence, neurostimulation, chronic pain, PTSD, Traumatic Brain Injury, medical device, neurosurgery
|
Austin |
TX |
| Valencell, Inc. |
Seamless energy balance monitor |
energy, balance, calories, fitness, obesity, caloric, metabolism, sensor
|
Raleigh |
NC |
| ImmersiveTouch, Inc. |
SENSIMMER Virtual Phaco Trainer for Cataract Surgery |
cataract surgery, phacoemulsification, capsulorhexis, patient safety, haptics, virtual reality
|
Westmont |
IL |
| SIGA Technologies, Inc. |
Small Molecule Inhibitors of Smallpox Virus Replication |
antiviral, smallpox, ST-246, egress inhibitor, biodefense, high throughput screen
|
Corvallis |
OR |
| CardioMend LLC |
Stentless semilunar heart valve reconstruction |
heart valve, autologous tissue, pericardium, semilunar, tissue testing
|
Santa Barbara |
CA |
| Sarawak MediChem Pharmaceuticals, Inc. |
SYNTHESIS OF NEW ANTIHIV AGENTS RELATED TO CALANOLIDE A |
HIV, Clinical Trials, NNRTI, resistance, in vitro, in vivo, calanolide, natural product
|
Woodridge |
IL |
| Stellar Biotechnologies, Inc. |
Technology for Culture of Megathura Crenulata for KLH |
KLH, hemocyanin, Megathura, Limpet, cancer, vaccine, aquaculture, immunostimulatory
|
Port Hueneme |
CA |
| VisualShare, Inc. |
Teleconsultation and Quality Review in Child Maltreatment |
child abuse, child maltreatment, Image collaboration, quality review, peer review, telehealth, diagnosis, TeleCAM™
|
Salt Lake City |
UT |
| The Blindsight Corporation |
Text Detective |
computer vision, text detection, iOS, Android, blind, low vision, text reader
|
Berkeley |
CA |
| ViewPlus Inc. |
The Accessible Graphics Reader for Blind People |
tactile graphics, braille, blindness, dyslexia, accessibility, ink and braille, audio/touch, graphical information
|
Corvallis |
OR |
| Three Rivers Holdings, LLC |
The SmartWheel: Development of Wheelchair Pushrim Force and Measurement Device |
wheelchairs, wheelchair propulsion, wheelchair biomechanics, measurement, wheelchair positioning, wheelchair selection, wheelchair seating, insurance justification
|
Mesa |
AZ |
| Ripple Effects |
Training and assessment software to reduce risk and enhance protective factors in adolescents |
violence prevention, behavior training , software, substance abuse, truancy, adolescent risk factors, school failure, social-emotional skills
|
San Francisco |
CA |
| Archimage, Inc. |
U44 DK066724-03 |
serious games, video games, diabetes, obesity, prevention, physical activity, nutrition, children
|
Houston |
TX |
| Lexical Technology |
Voice Recognition Front-End to Cancer Knowledge Sources |
speech interface, voice prompts, dialog, conversational features
|
Alameda, |
CA |
| Culmini Inc. |
Web interactive patient guides for complex medical treatments |
kidney transplant, dialysis, hospital comparison, chronic kidney disease, end stage renal disease
|
Burlingame |
CA |
| Humanitas, Inc. |
Web Trials Information Exchange |
cancer clinical trials, handheld computers, distance learning, website, document management, proposal management, online meetings
|
Silver Spring |
MD |
| Lexical Technology |
Wireless, Pen-Based Front-End to Cancer Knowledge Sources. |
oncology, machine-readable, pen-based interface, on-line reference
|
Alameda |
CA |
| Applied Health Science |
Wound and Skin Intelligence System (TM) or WSIS (TM) |
Chronic wound, Pressure ulcer, Risk assessment, Pressure Sore Status Tool, WSIS
|
Seattle |
WA |
SBIR/STTR Program Successes Through 2002
SBIR/STTR Success Stories entered up through 2002 are shown below (most files in PDF format):
Fourth Annual U.S. Small Business Administration 1999 Tibbetts Awards ...recognizing SBIR technological innovation, economic impact and business achievements
Congratulations to the following NIH SBIR awardees who were recipients of the 1999 Tibbetts Awards! These prestigious, national awards, named for Roland Tibbetts, a former SBIR Program Manager who is acknowledged as "founding father of the SBIR Program," are made annually to those small firms, projects, organizations and individuals judged to exemplify the very best in SBIR achievement. The Tibbetts Awards are an initiative of the Office of Advocacy in the US Small Business Administration (SBA) now managed through the Office of Technology. A full list of winners is available electronically at http://www.sba.gov/sbir/tibbetts/toc.html. (Note: All files below are in PDF format.)
Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.
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