SBIR and STTR Success Story for
MBF Bioscience

(Information Posted/Updated on 01/30/2008)

MBF Bioscience
185 Allen Brook Lane
Suite 101
Williston, VT  05495

Contact:    Susan Hendricks, Ph.D.
Phone:      802-288-9290
Fax:          802-288-9002
Web Site:

Project Title:  Neurolucida, AutoNeuron, Stereo Investigator, NeuroInformatica, 3D Virtual Slice
Related Award(s):  MH72063, MH062840, MH076188
Technology Developed:
MBF Bioscience has pioneered computerized microscopy tools for morphometric and quantitative analysis in neuroscience. The systems produced by MBF have made important contributions to scientific research worldwide. With its first NIH SBIR grant in 1989 MBF created the Neurolucida system. Today, Neurolucida is in use in over 1000 laboratories around the world and has become the gold standard tool for neuron tracing and brain mapping. In 1995 MBF received an SBIR award to create Stereo Investigator, which has become the most widely used system for stereology. MBF has also created other products funded by the NIH to enhance collaboration among researchers with Neuroinformatica, a tool for virtual slide image collaborative, archive and analysis. In 2004 we received a FastTrack award to create automated 3D and 2D neuron tracing software, called AutoNeuron.

Key Words:  stereology, morphometry, automated analysis, digital image archive, neuron reconstruction.
Uses of Technology/Products/Service:
Computerized microscopy tools are used in basic research, drug development and pharmaceutical fields to aid the quantification of objects viewed through the microscope.

Other Comments Related to Company's Success Story:
The continued support from NIH through the SBIR grant mechanism is a critical component of our business structure to fuel our research in software development and analytical methods for neuroscience and other biological sciences. In 2007, the company president, Jack Glaser, was honored as the "Vermont Small Business Person of the Year." Additionally, MBF Bioscience celebrates its twentieth year and has been selected as one of the "Best Places to Work in Vermont". Its products are now being used by scientists in 49 countries.