SBIR and STTR Success Story for
SAM Technology, Inc.

(Information Posted/Updated on 10/01/2004)

SAM Technology, Inc.
425 Bush Street, 5th Floor
San Francisco, CA  94108

Contact:    Alan Gevins
Phone:      415-837-1600
Fax:          415-274-9574
Web Site:

Project Title:  IMAGE VUE™ Neurophysiological and Neuroanatomical Visualization and Source Localization Software
Related Award(s):  N44 MH30023, R44 NS28623, R44 NS32241
Technology Developed:
IMAGE VUE™ is a wizard-driven software system, running under Windows XP, for co-registering EEGs with MRIs, performing patented DEBLURRING™ spatial enhancement and several types of source localization analysis, and interactive 3-D graphics visualization. The patented XCALIPER™ hardware and associated software facilitates rapid measurement of EEG electrode positions needed for co-registration with MRIs.

Key Words:  medical imaging, human brain, epilepsy, seizure localization, EEG, MRI, 3-D graphics.
Uses of Technology/Products/Service:
IMAGE VUE™ is used primarily to visualize and localize the origin and spread of epileptic seizures in the human brain in planning neurosurgical treatment of complex partial seizure disorders that are refractory to treatment with antiepileptic drugs.

Benefit to Company:
The SBIR program allowed us to develop a first-of-its-kind, turn-key software package for an important medical neurological niche market for which the economics did not justify private sector investment. In the course of developing IMAGE VUE™, we gained experience in making an easy-to-use specialized system, in developing software in accordance with FDA Good Manufacturing Practices, in registering a medical device with the FDA, and in negotiating an equitable distributor agreement with a company 100 times larger than ours. A number of competing products worldwide were modeled on IMAGE VUE™ .

How Product Was Commercialized:
IMAGE VUE™ is marketed to neurologists by Nicolet Biomedical, Inc., a subsidiary of VIASYS Healthcare (NYSE: VAS), and the world’s largest supplier to the clinical neurology market. See To date, Nicolet has purchased ~100 systems from us.

Other Comments Related to Company's Success Story:
We are very grateful to the peer-reviewers and NIH SBIR project officials for their support.