SBIR and STTR Success Story for
Illumina, Inc.

(Information Posted/Updated on 03/05/2004)

Illumina, Inc.
9885 Towne Centre Drive
San Diego, CA  92121

Contact:    Cynthia Allred
Phone:      858-202-4735
E-mail:      callred@illumina.com
Web Site:  http://www.illumina.com

Project Title:  Decoding Randomly- Assembled DNA Arrays
Related Award(s):  R21 HG01911
Technology Developed:
The project demonstrated the feasibility of decoding randomly assembled arrays of beads in wells. The decoding process is a crucial aspect of Illumina’s BeadArrayTM technology.

Key Words:  decoding, bead, random, oligonucleotide, fluorescence, microarray, snp genotyping, gene expression.
Uses of Technology/Products/Service:
The project enabled the manufacture of a novel type of microarray based on random assembly of beads in wells. This is called the BeadArrayTM technology. The arrays are highly miniaturized, robust and cost-effective. As a result, the project has enabled the development of a wide variety of applications based on BeadArray technology, including single nucleotide polymorphism (SNP) genotyping and gene expression profiling. Illumina sells genotyping and gene expression profiling systems that are based on decoded arrays, and also supplies the arrays and reagents as consumables for these high-throughput systems.

Other Comments Related to Company's Success Story:
By contributing to the development of a powerful new microarray platform, this project is having a broad impact in the commercial microarray marketplace. Illumina is providing new assays and technologies, based on decoded arrays, that are lowering costs and enabling large-scale experimentation for researchers in the United States and worldwide.

Past R&D and/or Sales from this Project:   $21 million