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ARCHIVED - NIH Grants Policy Statement (10/03)

NIH Grants Policy Statement



The National Institutes of Health Grants Policy Statement (NIHGPS) is intended to make available to NIH grantees, in a single document, the policy requirements that serve as the terms and conditions of NIH grant awards. This document also is designed to be useful to those interested in NIH grants by providing information about NIH—its organization, its staff, and its grants process. The NIHGPS is available online from the NIH home page at

NIHGPS Organization

The NIHGPS has three parts, which allows general information, application information, and other types of reference material to be separated from legally binding terms and conditions:

l      Part I: NIH Grants—General Information. Part I contains a glossary defining commonly used terms and abbreviations used throughout the document; describes NIH and its relationship to other organizations within the Department of Health and Human Services (HHS); specifies grantee, NIH, and other HHS staff responsibilities; outlines the grant application and review processes; and explains the various resources available to those interested in the NIH grants process.

l      Part II: Terms and Conditions of NIH Grant Awards. Part II includes generally applicable terms and conditions. This part also specifies the terms and conditions that apply to particular types of grants, grantees, and activities that differ from, supplement, or elaborate on the standard terms and conditions. These requirements, in separate sections, pertain to construction grants, research training grants and fellowships, modular applications and awards, conference grants, consortium agreements, grants to foreign and international organizations (and grants with substantial foreign components awarded to domestic organizations), grants to Federal institutions and payments to (or on behalf of) Federal employees, grants to for-profit organizations, and research patient care activities.

l      Part III: Points of Contact. Part III lists pertinent offices and officials with their addresses and telephone numbers.


Certain conventions are followed throughout this document. The term “grant” is used to mean both grants and cooperative agreements; however, for clarity, certain sections mention both grants and cooperative agreements. The term “grantee” generally is used to refer to recipients of grants and awardees of cooperative agreements; however the terms “recipient” or “awardee” also are used. “NIH” may be used in this document to refer to the entire organization or to its component organizations, or else to contrast an action by NIH, including actions by its ICs, with an action by a grantee or other organization. A reference to “Part II” or “Part III” without further elaboration means the corresponding part of the NIHGPS.


The NIHGPS was originally published with an effective date of October 1, 1998. It was subsequently revised with an effective date of March 1, 2001. This revision of the NIHGPS, which is an update of the 2001 publication, has an effective date of December 1, 2003. It applies to all NIH grants and cooperative agreements for budget periods beginning on or after December 1, 2003. It remains largely unchanged; however, it incorporates several new and modified requirements, clarifies certain policies, and emphasizes policies that require increased attention by grantees on the basis of recent developments. A number of the changes are ones that have been published since March 2001 as notices in the NIH Guide for Grants and Contracts; others implement recent changes in statutes, regulations, and policies. An explanation of the major changes from the March 2001 NIHGPS is included in the NIH Guide for Grants and Contracts notice announcing the reissuance of the NIHGPS.


OPERA develops and maintains this document. Changes in statutes, regulations, or policies that take effect before the next revision of the NIHGPS will be published separately in the NIH Guide for Grants and Contracts. Grantees are responsible for reviewing the NIH Guide for Grants and Contracts, which is published on the NIH home page at, for changes and for implementing them, as appropriate.

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